红参炮制加工中的皂苷水解反应及其产物的研究  

Study on Hydrolysis Reaction of Ginsenoside and Products in Red Ginseng Processing

作　　者：李向高[1] 富力[1] 鲁歧[1] 李想[1] 

机构地区：[1]吉林农业大学中药材学院,长春130118

出　　处：《吉林农业大学学报》2000年第2期1-9,共9页Journal of Jilin Agricultural University

基　　金：国家自然科学基金!资助项目 (No 3 90 0 982 )

摘　　要：选取鲜人参根制成匀浆 ,加入被研究的目标皂苷 (M Rb1、Rb1、Re、Ro) ,研究鲜人参中天然皂苷在生产加工实践中的水解变化。采用HPLC对 10种人参皂苷标品建立标准图谱和分离条件 ,然后对上述加工前后的目标皂苷 (M Rb1等 )、鲜人参浆、不同目标皂苷 +鲜人参浆等一系列样品进行定性、定量测定。结果表明 :在加工红参全过程中 ,人参二醇型 (panaxadiol type)丙二酸单酰基人参皂苷Rb1(简称M Rb1)主要被水解转化为 2 0S 人参皂苷Rg3 和Rb1,其次为人参皂苷Rd和Rh2 。其水解转化率依次为 2 6 15 %、2 5 2 3%、0 2 0 %、0 0 0 1%。人参三醇型 (panaxatriol type)中的人参皂苷Re水解生成人参皂苷Rg2 、Rh1和Rg1,其总转化率依次为 48 73%、11 2 8%、0 0 0 2 %。Root fresh ginseng and homogenate fresh ginseng adding investigation to know destination ginsenoside Hydrolysis reaction changes of natural ginsenoside in ginseng to find out First creation standard diagram pattern and isolation condition of HPLC analysis with regard to 10 class standard ginsenoside Then with regard to above mentioned destination ginsenoside (malonyl ginsenoside Rb 1, ginsenoside Rb 1, Re, Ro ) and homogenate fresh ginseng and homogenate fresh ginseng adding M Rb 1 and homogenate adding Rb 1 and homogenate adding Re and homogenate adding Ro, they uni series exponents of processing anterior and subsequence to use nature and quantitative analysis Result showed that panaxadiol type malonyl gisenoside Rb 1 hydrolysis conversion to become ginsenoside Rg 3, Rb 1, Rd and Rh 2 , they hydrolysis transformation efficiency to leave in order 26 15%, 25 23%, 0 20% and 0 001% Panaxatriol type ginsenoside Re hydrolysis production ginsenoside Rg 2, Rh 1 and Rg 1, they transformation efficiency to leave in order 48 73%,11 28%,0 002% 。

关 键 词：鲜人参 红参 水解产物 皂苷 炮制加工 

分 类 号：R284.2[医药卫生—中药学] R282.710.2[医药卫生—中医学]