疏肝和胃方治疗非糜烂性胃食管反流病临床观察  

Clinical observation of "Shugan Hewei Decoction" for non-erosive gastroesophageal reflux disease

作　　者：程艳梅[1,2] 张秀莲[1,2] 刘春芳[1,2] 孙永顺[1,2] 曹会杰[1,2] 朱生樑[1,2] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院消化科,上海200437 [2]上海中医药大学脾胃病研究所,上海200032

出　　处：《上海中医药杂志》2013年第6期48-49,共2页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市卫生局中医药科研青年基金项目(2010QJ023A);上海市教委脾胃病重点学科项目(JS0305)

摘　　要：目的观察疏肝和胃方治疗非糜烂性胃食管反流病的临床疗效。方法将60例非糜烂性胃食管反流病患者随机分为中药组和西药组(每组30例),分别予疏肝和胃方和奥美拉唑治疗;两组疗程均为8周,观察临床疗效及临床症状体征积分变化情况。结果中药组、西药组总有效率分别为93.3%、86.7%;组间临床疗效比较,差异有统计学意义(P<0.001)。两组治疗后临床症状体征积分均明显降低(P<0.001);组间治疗后比较,差异有统计学意义(P<0.001)。结论疏肝和胃方能够有效改善非糜烂性胃食管反流病患者的临床症状。Objective To observe the clinical efficacy of ＂Shugan Hewei Decoction＂ in treating non-erosive gastroesophageal reflux disease（GERD）.Methods Sixty cases were randomly divided into two groups： Chinese medicine group in which 30 cases were treated by ＂Shugan Hewei Decoction＂,and control group in which 30 cases were treated by Omeprazole（OME）,with the course of 8 weeks.The clinical efficacy and symptom score were observed.Results The total effective rate was 93.3% in the Chinese medicine group and 86.7% in the control group,with a difference between the two groups（P0.001）.After treatment,the symptom score markedly decreased in both two groups（P0.001）,and with significant difference between the two groups（P0.001）.Conclusion ＂Shugan Hewei Decoction＂ is effective to improve the clinical symptoms in patients with non-erosive GERD.The clinical efficacy of ＂Shugan Hewei Decoction＂ is better than the Omeprazole.

关 键 词：非糜烂性胃食管反流病 中医药疗法 疏肝和胃方 

分 类 号：R571[医药卫生—消化系统]