抗FMDV基因疫苗的研究进展  

Progress of genetic vaccines against foot-and-mouth disease virus

作　　者：严亨秀[1] 唐冬梅[1] 付丽新[1] 

机构地区：[1]西南民族大学生命科学与技术学院,成都610041

出　　处：《西南民族大学学报（自然科学版）》2013年第4期495-500,共6页Journal of Southwest Minzu University(Natural Science Edition)

基　　金：四川省科技厅项目:2011JY0033;西南民族大学研究生学位点建设项目(2011XWD-S0906)

摘　　要：口蹄疫是由口蹄疫病毒引起的猪、牛、羊等偶蹄动物一种高接触性传染病.口蹄疫一旦爆发和流行,会使家畜生产性能降低,给养殖户造成重大损失,给公共卫生造成重大的影响.随着弱毒苗禁用和灭活苗的减少使用,新型疫苗的研究成为热点.自1990年首次出现基因疫苗的研究报道之后,基因疫苗已经成为疫苗研究领域中的一大热点,因此该文对近年来国内外口蹄疫基因疫苗研究的主要进展进行综述.Foot-and-mouth disease （FMD） is a highly contagious disease of cloven-hoofed animals caused by FMD virus （FMDV）, including pigs, cattle and sheep. The outbreak and prevalence of FMD will decrease the production performance of livestock, reduce the economic outcomes to farmers and also harm the public health. With the potential risks of FMD attenuated vaccine and inactivated vaccine, it is advantageous to develop novel vaccines to reduce these elements of risk, including FMD genetic engineering subunit vaccine, synthetic peptide vaccine and gene vaccine. Since the FMD genetic vaccine was reported firstly in the early 1990s, it has become the hot research point. This review summarizes the main progress in the study ofgene vaccine.

关 键 词：口蹄疫 FMDV 基因疫苗 

分 类 号：S852.65[农业科学—基础兽医学] S855.3[农业科学—兽医学]