放大内镜智能分光比色成像对幽门螺旋杆菌感染时胃黏膜改变的分析  

Analysis of gastric mucosal changes with Hp infection by magnifying Fujinon intelligent chromoendoscopy

作　　者：肖玲[1] 阮巍山[1] 杨玉宇[1] 徐莉[1] 

机构地区：[1]广东省中山市人民医院消化内科,528400

出　　处：《中华消化病与影像杂志（电子版）》2013年第2期10-12,共3页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

摘　　要：目的探讨放大内镜智能分光比色成像下观察胃黏膜的改变在诊断幽门螺杆菌感染中的可行性及临床价值。方法 78例行放大胃镜窄带成像检查患者作为研究对象,应用快速尿素酶法、组织切片法、14C尿素呼气试验方法检测幽门螺杆菌感染情况,对幽门螺杆菌感染阳性患者进一步行放大内镜智能分光比色成像下胃黏膜的改变检测。结果14C尿素呼气试验、快速尿素酶试验、改良Giemsa染色组织切片法检测幽门螺杆菌感染阳性率分别为(48/30,61.54%)、(56/22,71.79%)、(54/24,69.23%),放大内镜智能分光比色成像下胃黏膜集合小静脉表现为消失型和不规则型的幽门螺杆菌感染率分别为(35/42,83.30%)、(38/42,90.50%),明显高于规则型(3/42,7.10%)。结论放大内镜智能分光比色成像直视下诊断幽门螺杆菌是一种较理想的、应用前景广阔的检测幽门螺杆菌的方法,值得在临床推广应用。Objective To investigate the feasibility and clinical value of magnifying Fujinon intelligent chromoendoscopy （FICE） in observing the gastric mucosal changes with helicobacter pylori （Hp） infection. Methods Hp infections were detected by rapid urease test, tissue slice method and ^14C urea breath test in 78 patients who had accepted magnifying endoscopy narrow-band imaging examination. Then, Hp positive patients accepted magnifying FICE to observe the changes of gastric mucosal. Results Respectively, the positive detection rates of ^14C urea breath test, rapid urease test and tissue slice method are 61.54% （30/48）, 71.79% （22/56） and 69.23% （24/54）. Furthermore, through magnifying FICE, Hp infection rates of gastric mucosa venules disappeared type （83.30%, 35/42） and irregular type （90. 50%, 38/42） were significantly higher than regular type （7.10%, 3/42）. Conclusions Magnifying FICE is an ideal and promising method in the detection of Hp infection under the direct-view which is worth to be spread in clinical application.

关 键 词：螺杆菌 幽门 胃镜检查 胃黏膜 智能分光比色 

分 类 号：R57[医药卫生—消化系统]