肾上腺皮质嗜酸细胞癌7例临床病理分析  

Clinical and pathological analysis of 7 cases of adrenocortical oncocytic carcinoma

作　　者：许敬平[1] 吴大为 黄江梅[3] 高艳明[4] 邵俊涛[5] 

机构地区：[1]秦皇岛市第一医院老年病科,066000 [2]河北港口集团港口医院肿瘤科,秦皇岛066000 [3]秦皇岛市第一医院病理科,066000 [4]北京大学第一医院内分泌科,北京100034 [5]秦皇岛市第一医院超声科,066000

出　　处：《临床与实验病理学杂志》2013年第7期765-768,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的探讨7例肾上腺皮质嗜酸细胞癌临床及病理特点。方法回顾性分析7例肾上腺皮质嗜酸细胞癌的临床特点、组织形态学特征,并复习相关文献。结果 7例肾上腺皮质癌中皮质醇增多症1例,原发性醛固酮增多症2例,无功能性4例。7例均为肾上腺超声诊断,术后病理诊断均为肾上腺皮质嗜酸细胞癌。6例进行随访,随访时间(21.7±20.6)个月,死亡3例。结论肾上腺皮质嗜酸细胞癌罕见,诊断依据病理学及免疫表型,多为无功能性(57.1%),亦可表现内分泌功能异常(42.9%),非低恶性度肿瘤,治疗以手术为主。Purpose To report 7 cases of adrenocortical oncocytic carcinoma, and to analysis their clinical and pathological features. Methods The clinical features and morphological characteristics of 7 cases of adrenocortical oncocytic carcinoma cell were analysed retrospectively, and the revelant literatures were reviewed. Results The 7 cases of adrenocortical carcinoma patients included 1 case of crushing＇ s syndrome, 2 cases of primary aldosteronism and 4 cases of nonfunction. All of the 7 cases were diagnosed by adrenal ul- trasonography, and postoperative pathologic diagnosis were adrenocortical oncocytic carcinoma. The 6 cases were followed up for （21.7 ＋ 20. 6） months, 3 patients died. Conclusion The adrenocortical oncocytic carcinoma is very rare, the diagnosis is based on pathol- ogy and immunohistochemistry, mostly is non-functional （ this group accounted for 57. 1% ） , but can also be showed endocrine dys- function （ this group accounted for 42. 9% ）. It is a low-grade malignant tumor and the main treatment is surgery.

关 键 词：肾上腺皮质肿瘤 肾上腺癌 嗜酸细胞癌 

分 类 号：R736.6[医药卫生—肿瘤]