藏药前列宁胶囊质量标准的研究  

Study on Quality Standard for Tibetan Medicine of Qianliening Capsule

作　　者：马宏伟 邵成雷 魏永义 孙绪丁 

机构地区：[1]山东阿如拉药物研究开发有限公司,山东济南250101

出　　处：《中国医学创新》2013年第20期129-132,共4页Medical Innovation of China

摘　　要：目的:研究并提高藏药前列宁胶囊的质量标准。方法:采用薄层色谱法鉴别红花、诃子、菥蓂子、藏茜草;采用高效液相色谱法同时测定没食子酸和羟基红花黄色素A。结果:薄层色谱显色清晰,阴性对照无干扰。没食子酸在33.76～337.6μg/ml浓度范围内线性关系良好,r=0.9996,平均加样回收率为98.35%,RSD为1.36%。羟基红花黄色素A在2.68～26.80μg/ml浓度范围内线性关系良好,r=0.9998,平均加样回收率为99.03%,RSD为0.72%。结论:该方法简便、可行、可靠,可用于控制前列宁胶囊的质量。Objective：To study and upgrade the quality standard of Tibetan Medicine Qianliening Capsule.Method：TLC method was used to identify Flos Carthami,Terminalia Chebula,Semen Thlaspi and Radix et Rhizoma Rubiae;Hplc was used for the determination of Gallic acid and Hydroxy Safflor yellow A.Result：Flos Carthami,Terminalia Chebula,Semen Thlaspi and Radix et Rhizoma Rubiae could be identified by TLC without the interference of negative control.Gallic acid and Hydroxy Safflor yellow A could be determined at the same time.Gallic acid was linear in the concentration range of 33.76-337.6μg/mL, r =0.9996.The average recovery rate was 98.35%,RSD=1.36%;Hydroxy Safflor yellow A had a good linear in the concentration range of 2.68-26.80 μg/ml, r =0.9998.The average recovery rate was 99.03%,RSD=0.72%.Conclusion：The method is simple, feasible,reliable,and can be effectively used for the quality control of Qianliening Capsule.

关 键 词：前列宁胶囊 红花 诃子 菥蓂子 藏茜草 没食子酸 羟基红花黄色素A 

分 类 号：R29[医药卫生—民族医学]