746例肝脏和肝内胆管肿瘤临床发病特点分析  

Clinical features of patients with liver neoplasm:An analysis of 746 cases

作　　者：桑伟[1] 哈德提.别克米托夫 陈兰[2] 何方平[2] 王成辉[1] 张巍[1] 李新霞[1] 

机构地区：[1]新疆医科大学第一附属医院病理科,乌鲁木齐市830054 [2]新疆医科大学第一附属医院肝病科,乌鲁木齐市830054

出　　处：《实用肝脏病杂志》2013年第4期338-340,共3页Journal of Practical Hepatology

基　　金：新疆维吾尔自治区科技支疆项目(项目编号:201291172);新疆维吾尔自治区科技支撑计划项目(项目编号:201233142)

摘　　要：目的探讨肝脏和肝内胆管肿瘤的临床发病特点。方法收集2003年~2011年我科诊断的肝脏和肝内胆管肿瘤746例，分析其发病特点。结果肝脏肿瘤发病位于前九位的依次为肝细胞癌（43.4%）、血管瘤（37.3%）、肝内胆管细胞癌（5.8%）、转移性肿瘤（3.8%）、造血和淋巴样肿瘤（1.1%）、胆道乳头状瘤病（0.94%）、局灶性结节状增生（0.94%）、肝细胞不典型增生（0.67%）和不典型增生结节（0.54%）；本组未发现孤立性纤维肿瘤、淋巴管瘤病、假脂肪瘤、胚胎性肉瘤、Kaposi肉瘤、上皮样血管内皮细胞瘤、血管肉瘤、癌肉瘤、横纹肌肉瘤、畸胎瘤、卵黄囊瘤和横纹肌样瘤；肝细胞癌的发病年龄高峰在40~69岁，男性比女性高发，肝内胆管细胞癌高发年龄为50~69岁，男性与女性发病人数相当；血管瘤发病年龄高峰为30~49岁，女性比男性高发；转移性肿瘤发病高峰为40~59岁，男性与女性发病人数相当。结论肝脏肿瘤发病有逐年递增的趋势，来源于上皮的肝细胞癌是肝脏最常见的恶性肿瘤，来源于间叶的血管瘤是最常见的良性肿瘤。Objective To investigate the clinical features of patients with liver neoplasms. Methods 746 patients with liver neoplasms were collected in our department from 2003 to 2011. Results The common diagno-sis was hepatocellular carcinoma（43.4%）,hemangioma（37.3%）,intrahepatic bile duct carcinoma（5.8%）,metastatic tumor（3.8%）,hematopoietic and lymphoid tumors（1.1%）,biliary papilloma disease（0.94%）,focal nodular hyperplasia （0.94%）,liver cell atypical hyperplasia （0.67%） and atypical hyperplasia nodules （0.54%）;we did not find mes-enchymal tumors such as solitary fibrous tumor,lymphangioma disease,false lipoma,embryonal sarcoma,Kaposi sar-coma,epithelioid hemangioendothelioma,angiosarcoma,carcinosarcoma,rhabdomyosarcoma, teratoma,yolk sac tumor and striated muscle tumor;the peak age of hepatocellular carcinoma was in 40 to 69 years old,and it was com-mon in men than in women; the peak age of intrahepatic bile duct carcinoma was in 50 to 69 years old,and it occurred both in men and in women;the peak age of hemangioma was in 30 to 49 years old,and it occurred more common in women than in men;the peak age of metastatic tumors was 40 to 59 years old,and men and women had the same incidence. Conclusion The incidence of liver neoplasm is increasing,and hepatocellular carcinoma is still the most common malignant tumor,and hemangioma is the most common benign tumor.

关 键 词：肝脏肿瘤 肝内胆管肿瘤 临床特征 

分 类 号：R735.7[医药卫生—肿瘤]