原发性双侧乳腺癌36例临床诊治分析  

Analysis on clinical outcomes of 36 patients with bilateral primary breast cancer

作　　者：崔殿龙[1] 解百宜[1] 胡蒙[1] 包传恩[1] 陈玉强[2] 

机构地区：[1]厦门大学附属成功医院(解放军第174医院)肿瘤外科,福建厦门361003 [2]厦门大学附属成功医院(解放军第174医院)肿瘤内科,福建厦门361003

出　　处：《临床军医杂志》2013年第7期670-672,共3页Clinical Journal of Medical Officers

基　　金：福建省科技厅自然科学基金资助课题(2010D013)

摘　　要：目的分析原发性双侧乳腺癌的临床特征。方法对2000年1月—2011年12月本院36例原发性双侧乳腺癌的临床资料进行回顾性分析。结果2例失访，健在并无瘤生存21例，非肿瘤死亡5例，乳癌复发死亡7例，其他肿瘤死亡1例，第2癌术后生存10年以上2例，5～10年17例，3～5年7例，1～3年8例。结论对具有双侧乳腺癌发病易感因素的患者应建立有效的随访制度和健康教育；第2癌应当按照单侧乳腺癌的治疗方案进行治疗；ER阳性患者都应积极行内分泌治疗。Objective To analyze the clinical feature of bilateral primary breast cancer （BPBC）. Methods A total of 36 patients with BPBC surgically treated in our hospital from Jan 2000 to Dec 2011 were retrospectively analyzed. Results Two patients were lost. Of the other patients （ n = 34 ） , 21 continued to survive without tumor,5 died of non-carcinoma,7died of breast cancer recurrence and 1 died of additional cancer. As for the survival duration, there were 2 patients who survived over 10 years after the operation for the second cancer, 17 ones who survived 5 through 10 years, 7 ones who survived 3 through 5 years, and 8 ones who survived 1 through 3 year（s）. Conclusion Close follow-up and heahh education should be considered in the patients with BPBC. It is sugges- ted that the treatment of second carcinoma be carried out similarly with unilateral breast cancer. All the patients with positive ER ex- pression should be treated by endocrine therapy.

关 键 词：双侧乳腺癌 易感因素 内分泌治疗 

分 类 号：R737.9[医药卫生—肿瘤]