葡萄膜炎患者黄斑区光相干断层扫描图像特征分析  

Characteristics of macular optical coherence tomography changes

作　　者：王桂敏[1] 崔彦[1] 王兴荣[1] 李洋[1] 刘婷婷[1] 王影[1] 毕宏生[1] 

机构地区：[1]山东中医药大学附属眼科医院,济南250002

出　　处：《中华眼底病杂志》2013年第4期380-383,共4页Chinese Journal of Ocular Fundus Diseases

基　　金：基金项目：国家自然基金（81072961,81100658）;山东省自然科学基金（ZR2010HM048）

摘　　要：目的观察葡萄膜炎患者黄斑区病变光相干断层扫描（OCT）图像特征。方法2011年5月至2012年5月临床明确诊断的葡萄膜炎患者51例78只眼纳入研究。其中，男性28例，女性23例；平均年龄（46．75±13．22）岁；病程1～24个月。前葡萄膜炎16例21只眼；小柳一原田综合症12例23只眼；Behqet病6例10只眼；交感性眼炎5例5只眼；其他后葡萄膜炎12例19只眼。患眼均行常规眼科检查及频域OCT检查，典型图像存盘分析。根据检查结果将黄斑区病变分为黄斑水肿、黄斑前膜形成、浆液性神经上皮脱离、黄斑区萎缩、黄斑板层裂孔、脉络膜新生血管（CNV）。结果78只眼中，黄斑区水肿48只眼，占患眼的61．5％。其中，黄斑囊样水肿33只眼；黄斑弥漫性水肿15只眼。黄斑前膜22只眼，占患眼的28．2％。脉络膜新生血管4只眼，占患眼的5．1％。黄斑裂孔4只眼，占患眼的5．1％。黄斑萎缩10只眼，占患眼的12．8％。浆液性神经上皮脱离22只眼，占患眼的28．2％。结论葡萄膜炎患者黄斑区OCT表现具有多种形态特征。Objective To observe the characteristics of optical coherence tomography （OCT） of the macular in uveitis patients. Methods A total of 51 cases （78 eyes） of uveitis admitted to affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine from May 2011 to May 2012 were reviewed retrospectively. All patients were underwent OCT examination and classified according to characteristics of OCT. Results The characteristics of OCT in uveitis were classified into six groups. Macular edema including cystoid macular edema and diffuse edema was detected in 48 eyes （61.5 %）. Macular epiretinal membrane was found in 22 eyes （28.2%）. Choroidal neovascularization and macular hole was found in 4 eyes （5.1%）, respectively. Ten eyes （12.8%） showed maeular atrophy and 22 eyes （28.2%） showed serous neuroepithelium detachment. Conclusions Macular OCT in uveitis patients displayed different morphological characteristics.

关 键 词：葡萄膜炎 诊断 体层摄影术 光学相干 诊断显像 

分 类 号：R77[医药卫生—眼科]