口腔癌患者术后生存质量的影响因素分析  

Related Factors of Quality of Life in Oral Cancer Patients After Operation

作　　者：王维[1] 池宇峰[1] 刘洁如[1] 谭锡涛[1] 

机构地区：[1]广东医学院附属韶关市第一人民医院口腔颌面外科,广东韶关512000

出　　处：《武汉大学学报（医学版）》2013年第4期585-587,共3页Medical Journal of Wuhan University

摘　　要：目的:探讨影响口腔癌患者术后生存质量(QOL)变化及其相关影响因素。方法:选择65例在韶关市第一人民医院口腔颌面外科手术治疗的口腔癌患者,采用华盛顿大学生存质量问卷(UW-QOL)测量口腔癌患者术前和术后12个月的QOL,利用SPSS18.0软件包对数据进行统计学分析。结果:术后12个月,无瘤生存者的QOL显著高于复发患者;早期口腔癌患者功能性颈清扫术的QOL高于根治性颈清扫术;中、晚期口腔癌患者行修复性功能性外科和病灶根治性切除术的QOL明显高于单纯性病灶根治性切除术;婚姻状况、临床分期及术后放疗影响患者的QOL。结论:保存胸锁乳突肌、副神经可避免肩痛及臂外展功能障碍、降低复发率、减少术后放疗的并发症、修复性功能性外科的应用、增加社会和家庭关爱及必要的辅助治疗可提高口腔癌患者术后的QOL。Objective： To investigate the changes and related factors of quality of life （QOL） in patients with oral cancer after operation. Methods： A total of 65 patients with surgical treatment of oral cancer patients were included in this study. The QOL of thes patients preoperation and 12 months after operation were assessed by the University of Washington Quality of Life （UW-QOL）. All data were analyzed by SPSS 18.0 software package. Results： After 12 months, the postoperative QOL was higher in the patients without recurrence （vs patients with recurrence）, in functional neck dissection patients（vs radical neck dissection patients）, and in reparative functional surgery and radical resection patients （vs simple lesions radical resection patients） with intermediate and late oral cancer. Marital status, clinical stage and postoperative radiotherapy had influence on pa- tients＇ QOL. Conclusion： Measures such as saving sternocleidomastoid muscle and accessory nerve which can avoid shoulder pain and arm abduction dysfunction, decreasing the recurrence rate and postoperative radiotherapy complications, application of reparative function surgery, social and family care, and necessary auxiliary treatment can improve the QOL in patients with oral cancer.

关 键 词：生存质量 口腔癌 因素 UW-QOL 

分 类 号：R739.8[医药卫生—肿瘤]