MIC-1在肠瘤与肠癌组织中的表达及其意义  

Expression of Macrophage Inhibitory Cytokine-1(MIC-1)in intestinal tumor and colorectal cancer and their clinic significance

作　　者：李倩[1] 蒋军林[2] 

机构地区：[1]湖南省马王堆医院中医科,湖南马王堆410016 [2]湖南省中医药研究院附属医院脑病科,湖南长沙410006

出　　处：《中外医疗》2013年第18期21-22,共2页China & Foreign Medical Treatment

基　　金：湖南省科技计划项目(2009sk3068)

摘　　要：目的探讨MIC-1在肠瘤中的表达以及在晚期肠癌组织中的表达及其临床意义。方法采用免疫组织化学法分别检测34例肠瘤患者和34例肠癌患者组织中MIC-1的表达。结果肠癌组MIC-1的IOD值为(6.00±1.09),肠瘤组MIC-1的IOD值为(4.36±1.33),肠癌组高于肠瘤组(P<0.01)。结论提示随着疾病性质由肠瘤向肠癌的转变,MIC-1的表达呈升高趋势,推断MIC-1的表达增加将提示肠瘤癌变风险增加。Objective To investigate the expression of MIC-1 in intestinal tumor and colorectal cancer patients and their clinic significance.Methods Using the immunohistochemical method to test the expression of MIC-1 in 34 advanced colorectal cancer and in 34 intestinal tumor patients.Results The IOD of MIC-1 in colorectal cancer group were（6.00±1.09）,witch was higher than intestinal tumor group with IOD were（4.36±1.33）（P0.01）.Conclusion With the course of disease from intestinal tumor transformation to colon cancer,the expression of MIC-1 was increased,and we Infered that the increased expression of MIC-1 will prompt the intestinal tumor carcinogenesis risk increase.

关 键 词：肠瘤 肠癌 MIC-1 

分 类 号：R735.37[医药卫生—肿瘤]