艾滋病神经系统损害的脑部及脊髓影像学改变探讨  

Neuro-imaging changes of brain and spinal lesions in AIDS patients with nervous system damage

作　　者：古坤意[1] 潘秋燕[1] 邹良玉[1] 

机构地区：[1]暨南大学第二临床医院(广东深圳市人民医院),深圳518020

出　　处：《中国实用神经疾病杂志》2013年第13期1-3,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨艾滋病神经系统损害的脑部及脊髓影像学改变。方法对25例艾滋病伴神经系统损害患者包括脑部和脊髓损害进行影像学(CT或MRI)检查,分析其影像学特点。结果 25例有神经系统损害的艾滋病中表现脑部损害较为多见,影像学表现为3例颅内多发占位性病变;4例表现为进行性多灶白质脑病;11例隐球菌性脑病中4例表现为基底节多发小点片状低密度灶,2例有脑膜强化表现;其他无异常表现;4例表现为脑梗死;3例脊髓损害患者,其中1例表现为脊髓炎症改变,2例为后索损害表现为脊髓变细萎缩。结论艾滋病可引起神经系统不同部位及不同性质损害,在影像学上显示不同的非特征性改变。Objective To investigate neuro-imaging changes of brain and spinal lesions in AIDS patients.Methods To analyze and summarize the image features（CT or MRI） of 25 AIDS patients with nervous system damage,including damage to the brain and spinal cord.Results In 25 AIDS patients with nervous system damage,patients with brain damage were more than these with spinal cord damage.Among the image（CT or MRI） of 25 AIDS patients,space-occupying lesions were found in three patients,progressive multi-focal white matter disease was demonstrated in four patients.Multiple patch hypodense lesions in basal ganglion on brain were shown in four patients,emultiplenhancement in brain menix was found in two patients,and others were normal manifestations in 11 patients with cryptococcal infection.Four other patients had brain infarction.Among three patients with spinal lesion,inflammatory changes of spinal cord was found in one patients and another two patients were shown posterior cord atrophy.Conclusion AIDS Can induce different lesions in many parts of CNS,which has different non-characteristics in neuroimaging.

关 键 词：艾滋病 神经系统 影像学 

分 类 号：R747.9[医药卫生—神经病学与精神病学]