CIS患者OCSP分型及颅内血管狭窄危险因素分析  

Risk factors of intracranial vascular narrow in patients with cerebral ischemic stroke based on OCSP criteria

作　　者：秦平[1,2] 张镏琢[1] 李昂[1] 郑娟娟[1] 孙远洁[1] 袁重胜[3] 刘艳[1] 赵晓雯[4] 

机构地区：[1]哈尔滨医科大学卫生统计学教研室,黑龙江哈尔滨150081 [2]镇江市疾病预防控制中心信息科 [3]哈尔滨医科大学研究生院 [4]哈尔滨医科大学卫生经济教研室

出　　处：《中国公共卫生》2013年第8期1202-1204,共3页Chinese Journal of Public Health

基　　金：国家自然科学基金(30972537);黑龙江省自然科学基金(D201036)

摘　　要：目的探讨缺血性脑卒中(CIS)患者分型及颅内血管狭窄的危险因素,为预防脑卒中的再发提供参考依据。方法于2006年3月—2007年2月在哈尔滨医科大学附属第二医院神经内科对首次住院治疗的135例CIS患者进行经颅多普勒超声(TCD)检测,并进行牛津郡社区脑卒中项目(OCSP)分型,运用logistic回归模型分析颅内血管狭窄的危险因素。结果 135例CIS患者OCSP分型比例由大至小依次为后循环梗塞(31.85%)、腔隙性梗塞(31.11%)、部分前循环梗塞(25.93%)、完全前循环梗塞(11.11%);CIS患者颅内血管狭窄率为23.70%(32/135);多因素logistic回归分析结果表明,高血压病史、糖尿病病史、OCSP分型为完全前循环梗塞是CIS患者颅内血管狭窄的危险因素。结论 CIS患者应预防高血压、糖尿病等疾病的发生和发展,并及时给予OCSP分型,以便有针对性地防止颅内血管狭窄的发生及脑卒中的再发。Objective To explore risk factors for different types of intracranial vascular narrow in patients with cerebral ischemic stroke based on Oxfordshire Community Stroke Project（OCSP）classification criteria. Methods We recruited 135 first hospitalization patients with cerebral ischemic stroke from March 2006 to February 2007 in the Second Affiliated Hospital of Harbin Medical University and all the patients were examined with transcranial Doppler ultrasound（TCD）and classified according to OCSP criteria.Logistic regression model was used to analyze the risk factors of intracranial vascular narrow. Results Intracranial vascular narrowing rate was 23.70% among the patients which was mainly middle cerebral artery stenosis.History of hypertension,history of diabetes,and total anterior circulation infarct（TACI）classified based OCSP criteria were the risk factors of intracranial vascular narrow for the patients. Conclusion Cerebral ischemic stroke patients should pay more attention to the occurrence and development of high blood pressure and diabetes for the prevention of intracranial stenosis and the recurrence of ischemic stroke.

关 键 词：缺血性脑卒中 OCSP分型 颅内血管狭窄 经颅多普勒超声 危险因素 

分 类 号：R543[医药卫生—心血管疾病]