前后循环脑梗死危险因素、TOAST病因分型及预后分析  

Analysis on stroke risk factors, TOAST subtypes and prognosis in the anterior and posterior cir- culation infarction

作　　者：赵建民[1] 

机构地区：[1]河南省新乡市中心医院神经内一科,453000

出　　处：《中国实用医刊》2013年第15期19-21,共3页Chinese Journal of Practical Medicine

摘　　要：目的了解前后循环脑梗死患者常见的危险因素、病因分型及预后的差异，以利于进行针对性防治。方法连续收集前后循环脑梗死住院患者507例和114例，收集相关的危险因素，对其进行TOAST病因分型，在发病3个月和6个月后进行随访，对前后循环脑梗死中常见发病危险因素、类型及预后进行比较分析。结果高血压是前后循环脑梗死患者最常见的危险因素，分别占58．2％和63．2％，两组比较差异无统计学意义（P〉0．05）。前循环组中吸烟和高脂血症比例低于后循环组，房颤比例高于后循环组（P〈0．05）。前循环脑梗死中心源型栓塞型卒中比例高于后循环组（P=0．042）。后循环脑梗死患者在3个月和6个月的随访中病死率和预后不良发生率低于前循环组（P〈0．05）。结论前后循环脑梗死患者常见危险因素和病因分型存在着一定差异。前循环脑梗死患者3个月和6个月的预后较后循环脑梗死患者差，其结果需要进一步的研究来证实。Objective To study stroke common risk factors, TOAST subtypes and prognosis inthe anterior and posterior circulation infarction. Methods Five hundred and seven patients with anterior circulation infarction and 114 pa-tients with posterior circulation infarction were prospectively analyzed in common risk factors, TOAST subtypes and their prognosis. Results Hypertension was a major risk factor in anterior circulation infarc- tion and posterior circulation infarction （ 58.2% vs 63.2% ）, this difference was not statistically signifi- cant （ P 〉 0.05 ）. The prevalence of smoking and hyperlipidemia in anterior circulation infarction was low- er than the posterior circulation infarction, and the prevalence of atrial fibrillation in anterior circulation infarction was higher than that in posterior circulation infarction （P 〈 0. 05 ）. The prevalence of cardio- embolic strokes in anterior circulation infarction was higher than that in posterior circulation infarction （P = 0. 042）. At the end of 3 and 6 months follow-up, patients with anterior circulation infarction had higher matality rate and poorer prognosis rate than patients with posterior circulation infarction （P 〈 0.05）. Conclusions There are some differences in stroke common risk factors, subtypes and out- comes between anterior and posterior circulation infarction, patients with anterior circulation infarc- tion remained more diabled than patients with posterior circulation infarction, which needs to be veri- fied by future studies.

关 键 词：前循环脑梗死 后循环脑梗死 危险因素 病因分型 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]