脑卒中合并卵圆孔未闭临床及文献分析  

Clinical Analysis of Stroke Patients with Patent Foramen Ovale

作　　者：逯青丽[1] 韩海燕[2] 季苏琼[2] 熊永洁[2] 刘玲玲[2] 刘建[1] 朱遂强[2] 薛峥[2] 

机构地区：[1]华中科技大学同济医学院附属同济医院综合科,武汉430030 [2]华中科技大学同济医学院附属同济医院神经内科,武汉430030

出　　处：《神经损伤与功能重建》2013年第4期260-262,272,共4页Neural Injury and Functional Reconstruction

摘　　要：目的:探讨脑卒中合并卵圆孔未闭(PFO)患者的临床特征。方法:回顾性分析2002年1月~2012年11月我院收治的及万方数据库和中国医知网报道的脑卒中合并PFO患者41例的临床资料。结果:本组患者年龄<55岁35例(85.4%),有少量吸烟史9例,高血压5例,高血脂1例,糖尿病2例;左侧大隐静脉瓣膜功能不全1例,下肢深静脉血栓6例,髋关节置换术后2例;卵圆孔缺损直径≥2 mm者26例(86.7%);头颅MRI示皮质下白质额叶区、顶叶区梗死各12例。结论:脑卒中合并PFO患者发病年龄偏小,多无常规脑血管病危险因素,卵圆孔缺损直径≥2 mm易发病,确诊需经食管超声心动图、经颅多普勒超声造影等辅助检查。Objective：To study the clinical characteristics of stroke patients with patent foramen ovale （PFO）. Methods： The clinical data of 41 cases with stroke combined PFO were analyzed retrospectively. Results： In 41 cases, 35 （85.4%） cases were younger than 55 years old, 9 cases had history of smoking, 5 cases had hypertension, one had high cholesterol and 2 cases had diabetes. One had the valve insufficiency in left great saphenous vein, 6 cases had deep vein thrombosis in legs and 2 cases were after total hip arthroplasty. Twenty-six cases （86.7%） showed the PFO size larger than 2 mm. Each of 12 cases showed subcortieal lesions in the t^ontal or parietal lobes on brain MRI. Conclusion： Stroke patients with PFO are young （〈55 years） and most of them had no risk factors for cerebrovascular diseases. Patients with PFO larger than 2 mm have a higher prevalence of strokes. The transesophageal echocardiography or contrast-enhanced transeranial color doppler are necessary for the diagnosis.

关 键 词：脑卒中 卵圆孔未闭 

分 类 号：R741[医药卫生—神经病学与精神病学] R743.3[医药卫生—临床医学]