青年缺血性卒中的危险因素病因学特点及短期预后情况  

Ischemic stroke in young adults——risk factors and short-term prognosis

作　　者：胡艳兵[1] 胡蓓蕾[1] 邹明[1] 何志勇[1] 陈松芳[1] 赵丹[1] 王小同[1] 张雄[1] 

机构地区：[1]温州医学院附属第二医院神经内科,浙江温州325027

出　　处：《临床荟萃》2013年第7期738-741,共4页Clinical Focus

基　　金：温州市科技局科技计划项目(Y20070038)

摘　　要：目的探讨青年缺血性卒中的危险因素及病因学特点。方法回顾性分析于本院住院治疗的年龄18～50岁青年缺血性卒中患者153例,分析其危险因素、病因学特点、卒中部位、短期预后情况。结果高血压71例(46.4%)、糖尿病42例(27.4%)、高脂血症35例(22.9%)、吸烟11例(7.1%)、酗酒13例(8.4%)为常见的危险因素;经TOAST(Trial of Org 10172in Acute Stroke Treatment)病因学分型,依次为大动脉粥样硬化、小血管闭塞、心源性栓塞、其他已明确的卒中病因及不明病因的卒中。卒中部位均以基底节区多见,伴有多发灶的梗死亦较多见。绝大多数患者短期(发病30天)预后良好。结论高血压、糖尿病、高脂血症、吸烟、酗酒等传统的卒中危险因素仍为青年缺血性卒中主要原因。短期预后大多良好。Objective The aim of this study was to investigate the etiologic spectrum, subtypes and short-term outcomes of ischemic stroke in young adults. Methods We retrospectively reviewed the data of 153 patients aged 18 to 50 with ischemic stroke in a tertiary stoke unit. The risk factors, the distribution of stroke subtype and short-term outcomes were analyzed. Results There were high incidence of hypertension 71 patients（46.4%） ,diabetes mellitus 42 patients（27.4% ）, hyperlipidemia 35 patients （22.9%）, smoking 11 patients （7.1%） and alcohol abuse 13 patients （8.4 %）. Large-vessel atherosclerosls was found to be the main subtype of stroke, followed by small-vessel occlusion, cardioembolism,other determined causes, undetermined etiology according to the TOAST （Trial of Org 10172 in Acute Stroke Treatment）. Most patients had good outcome in the short-term prognosis （30 days from onset）. Conclusion Hypertension,diabetes mellitus,hyperlipidemia, smoking, alcohol abuse and other conventional risk factors are the most common risk factors in the ischemic stroke patients between 18-50 years of age. Short-term outcomes are favorable.

关 键 词：脑血管意外 发病年龄 危险因素 

分 类 号：R743[医药卫生—神经病学与精神病学]