超声造影在高强度聚焦超声治疗子宫肌瘤中的作用评价  

Contrast-enhanced Ultrasound in Treatment of Ultrasound-guided High Intensity Focused Ultrasound Ablation for Uterine Fibroids

作　　者：谢斌[1] 王亚琴[2] 左鹏[3] 张昕[4] 何敏[4] 何佳[4] 

机构地区：[1]黄冈市中心医院超声科,湖北省黄冈市438000 [2]黄冈市中心医院,湖北省黄冈市438000 [3]黄冈市中心医院磁共振室,湖北省黄冈市438000 [4]四川省遂宁市中心医院妇产科

出　　处：《中国超声医学杂志》2013年第8期754-757,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的通过与磁共振成像(MRI)结果比较,评价超声造影(CEUS)在高强度聚焦超声(HIFU)治疗子宫肌瘤过程中实时判断消融效果的价值。方法对72例子宫肌瘤患者92个肌瘤行HIFU治疗的同时行CEUS和MRI检查。结果 CEUS与MRI检查结果比较,治疗前肌瘤最大径,肌瘤体积,非灌注区体积,肌瘤消融率分别为(4.87±2.12)cm比(4.85±2.11)cm,(71.1±89.1)cm^3比(74.1±91.7)cm^3,(59.1±83.4)cm^3比(59.2±89.6)cm^3,(83.8±26.5)%比(83.1±21.6)%;2种检查方法所测定各指标间无统计学差异(P>0.05)。CEUS与术后MRI检查的各指标分别具有高度相关性。术中出现的所有副反应与CEUS无关。结论 CEUS是一种准确评价HIFU消融效果的方法,可安全用于HIFU术中实时评价子宫肌瘤消融效果。Objective To evaluate the role of contrast-enhanced ultrasound （CEUS） in the treatment of ultrasound-guided high intensity focused ultrasound （HIFU） for uterine fibroids. Methods A total of 72 patients with 92 uterine fibroids were both evaluated with CEUS and MRI during and after HIFU treatment. Results The size of fibroids, the volume, the non-perfused volume, and non-perfused volume ratio detected on CEUS vs. MRI were （4.87±2.12） cm vs. （4.85±2.11） cm, （71.1±89.1） cms vs. （74.1±91.7） cm3 , （59.1±83.4） cm3 vs. （59.2± 89.6） cm2 , （83.8±26.5） vs. （83.1±21.6）% ,respectively. No statistically difference was observed between them （P〈0.05）. The correlation analysis showed that there was close relationship between the results from CEUS and MRI. The adverse effects occurred in the treatment were not related to CEUS. Conclusions CEUS is an accurate method in assessing the treatment effect of HIFU and could be safely used during HIFU treatment for uterine fibroids.

关 键 词：子宫肌瘤 HIFU 消融 超声造影 

分 类 号：R737.33[医药卫生—肿瘤]