犬肋骨肌瓣环替代气管的实验研究  

Experimental circumferential tracheal replacement with rib and costal muscle ring in dog

作　　者：张旭[1] 张朝满[1] 李汝泓[2] 王笑茹[1] 辛国华[1] 林健[1] 云佩茹 周宝庆[1] 

机构地区：[1]承德医学院附属医院胸心外科,067000 [2]承德医学院附属医院麻醉科,067000

出　　处：《中国肺癌杂志》2000年第2期125-128,共4页Chinese Journal of Lung Cancer

基　　金：河北省卫生厅科研资金!(960 38)资助

摘　　要：目的　探讨应用犬自体带血管蒂的肋骨肌瓣环修复胸内长段环形缺损气管的可行性。方法　选用成年杂种犬 18只 ,将第三肋骨及上下肋间肌修整成带蒂的骨肌瓣环 ,以此来替代切除的气管环。结果　 18只犬术后存活 11只 ,生存时间最长的犬达 14个月。这些犬尽管再造气管环轻度狭窄 ,但可以自由活动。组织学检查显示肋间肌组织血供良好 ,环的内层胸膜间皮被纤毛上皮替代。结论　肋骨肌瓣环替代胸内气管具有操作简便、并发症少的特点。本研究结果提示该术式有望应用于临床。Objective To evaluate the feasibility of using vascularized rib and costal muscle ring to repair large circumferential defect of thoracic trachea in dog. Methods Eighteen adult mongrel dogs were used in this study. The third rib with adjacent intercostal muscles was engineered to a ring with vascular pedicle, which replaced five or eight rings of trachea. Results Eleven of eighteen dogs were alive after operation, and the longest one had survived for 14 months. These dogs were active, although a slight stricture at the newly formed trachea was found. Microscopic examination showed the trachea had good blood supply, and the substitution of pleural epithelium by ciliated epithelium was observed. Conclusion Circumferential tracheal replacement with vascularized rib and intercostal muscle ring is easily managed and has less complications. The results suggest that this technique might be clinically used in the future.

关 键 词：气管外科 气管成形 气管替代 肋骨肌瓣环 

分 类 号：R730.56[医药卫生—肿瘤]