单疱病毒性角膜炎伴发青光眼  

Herpes simplex keratitis associted with glaucoma

作　　者：王琳[1] 蔡如超[1] 邓应平[1] 申光琴 

机构地区：[1]华西医科大学附一院眼科,61004

出　　处：《中国实用眼科杂志》2000年第8期483-485,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的 :探讨单疱病毒性角膜炎伴发青光眼的临床特点、发病机理与治疗方法。方法 :对 2 1例患者的临床资料及实验室检查结果进行分析。结果 :2 1例患者中 ,盘状角膜基质炎 15例 ;角膜色素膜炎 4例 ;拟青光眼睫状体炎 2例。共同的临床表现特点是 :在原角膜病变的基础上出现眼胀痛 ,结膜充血加重 ,角膜上皮弥漫性水肿及不同程度的色素膜眼体征 ,眼压升高多在 6 .6 5 k Pa以上。 PCR检测外周血单疱病毒 型 DNA阳性 4例 (19.0 5 % )。 2 1例患者经过抗病毒及抗炎治疗均获临床治愈。结论 :本组病例多系单疱病毒通过内生性感染导致小梁炎与色素膜炎引起眼压升高 ,通过积极的抗病毒与抗炎治疗能迅速控制炎症与眼压。To investigate clinical ferture pathogenesis and treatment mathods of herpes simplex keratitis (HSK)with glaucoma.Methods:We analyzed clinical materials and laboratorial assay of 21 patients.Ressults:21 cases included disciform keratitis 15 cases,keratovitis 4 cases and suspieious glaucomatocyclitis 2 cases.Features of their clinical menifestation werw pain and fulness,obvious conjestion,diffuse edema of epithlium,various degree uveitis,and increased intraocular pressure(over 6 65kPa) based on primary keratopathy.PCR of peripheral blood verified HSK type I DNA pastitive in 4 cases(19 05%).Clinical cure of 21 cases obtained by antiviral and anti inflammatary treatment.Conclusion:Glaucoma was caused by infective trabeculitis and Uveitis of herpes simplex virus.The inflammation and glaucoma could control through active anti viral and anti inflammatary treament.

关 键 词：单疱病毒性角膜炎 青光眼 并发症 临床特点 治疗 

分 类 号：R772.210.6[医药卫生—眼科] R775[医药卫生—临床医学]