阴道镜与宫颈环形电切术在宫颈上皮内瘤变诊断和治疗中的应用价值比较  

Application value of colposcopy and loop electrical excision procedure in diagnosis and treatment on cervical intraepithelial neoplasia

作　　者：孙淑华[1] 王少帅[2] 张庆华[3] 沈健[3] 贾瑶[2] 黄科程[2] 李雄[2] 袁静萍[3] 黄磊[3] 田训[3] 唐方徐[2] 周航[2] 周金[2] 孙海英[2] 陈苏芳[2] 王世宣[2] 邓东锐[2] 李双[2] 

机构地区：[1]湖北省肿瘤医院妇科肿瘤科,湖北武汉430071 [2]华中科技大学同济医学院附属同济医院妇产科,湖北武汉430030 [3]武汉市中心医院妇产科,湖北武汉430030

出　　处：《新乡医学院学报》2013年第8期629-631,共3页Journal of Xinxiang Medical University

基　　金：国家自然科学基金资助项目(编号:81101964;81172464);湖北省自然科学基金资助项目(编号:2012FFB02421);"重大新药创新"科技重大专项项目(编号:2009ZX09103-739)

摘　　要：目的比较宫颈上皮内瘤变(CIN)术前阴道镜下活组织检查结果与宫颈环形电切术(LEEP)后病理检查结果,评价阴道镜与LEEP在CIN诊断和治疗中的应用价值。方法对350例疑似CIN患者术前进行阴道镜下活组织检查病理诊断,并与LEEP术后组织病理检查结果进行对照比较。结果 350例手术均成功,阴道镜下活组织病理检查结果与LEEP术后病理检查结果完全符合率为72.57%,诊断过度率15.71%,诊断不足率11.71%。结论阴道镜下活组织检查可能遗漏CIN或早期浸润癌;LEEP可提供较完整的组织标本,可进一步筛查宫颈癌,有效弥补阴道镜的不足。Objective To compare the biopsy result by colposcopy before operation and pathology result after loop electrical excision procedure（LEEP） in cervical intraepithelial neoplasia（CIN）,and to evaluate the value of colposcopy and LEEP in diagnosis and treatment of CIN.Methods Biopsy by colposcopy before operation and biopsy after LEEP were analyzed and compared in 350 patients with skeptical CIN.Results The total coincidence rate of pathological results between cervical biopsy by colposcopy and LEEP was 72.57%,with 55 cases upgraded（15.71%） and 41 cases downgraded（11.71%）.Conclusion The biopsy by colposcopy may miss the CIN or early invasive carcinoma;LEEP can provide a more complete specimens,and further screening cervical cancer,and redeem the lack of colposcopy effectively.

关 键 词：宫颈上皮内瘤样病变 阴道镜检查 宫颈环形电切术 

分 类 号：R737.33[医药卫生—肿瘤]