An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV  

作　　者：ZHANG XiaoShuang LIU Yan ZHAO Li LI Bing YU Hao WEN HongLing YU Xue-Jie 

机构地区：[1]School of Public Health,Shandong University [2]University of Texas Medical Branch,Galveston,Texas 77555-0609,USA [3]Anhui Province Center for Disease Control and Prevention [4]Jinan Junqu Center for Disease Control and Prevention

出　　处：《Science China(Life Sciences)》2013年第8期697-700,共4页中国科学（生命科学英文版）

摘　　要：Severe fever with thrombocytopenia syndrome(SFTS) is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus,SFTSV,named after the disease.The transmission vectors and animal hosts of SFTSV are unclear.Ticks are the most likely transmission vectors and domestic animals,including goats,dogs,and cattle,are potential amplifying hosts of SFTSV.The clinical symptoms of SFTS are nonspecific,but major symptoms include fever,gastrointestinal symptoms,myalgia,dizziness,joint pain,chills,and regional lymphadenopathy.The most common abnormalities in laboratory test results are thrombocytopenia(95%),leukocytopenia(86%),and elevated levels of serum alanine aminotransferase,aspartate aminotransferase,creatine kinase,and lactate dehydrogenase.The fatality rate for SFTS is 12% on average,and the annual incidence of the disease is approximately five per 100000 of the rural population.Severe fever with thrombocytopenia syndrome （SFTS） is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus, SFTSV, named after the disease. The transmission vectors and animal hosts of SFTSV are unclear. Ticks are the most likely transmission vectors and domestic animals, including goats, dogs, and cattle, are potential amplifying hosts of SFTSV. The clinical symptoms of SFTS are nonspecific, but major symptoms include fever, gastrointestinal symptoms, myalgia, dizziness, joint pain, chills, and regional lymphadenopathy. The most common abnormalities in laboratory test results are thrombocytopenia （95%）, leukocytopenia （86%）, and elevated levels of serum alanine aminotransferase, aspartate ami- notransferase, creatine kinase, and lactate dehydrogenase. The fatality rate for SFTS is 12% on average, and the annual inci- dence of the disease is approximately five per 100000 of the rural population.

关 键 词：SFTSV TICK THROMBOCYTOPENIA LEUKOPENIA BUNYAVIRUS PHLEBOVIRUS hemorrhagic fever emerging infectious diseases 

分 类 号：R510[医药卫生—内科学]