BUNYAVIRUS

作品数：10被引量：90H指数：6
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Engineered biocontainable RNA virus vectors for non-transgenic genome editing across crop species and genotypes被引量：13
《Molecular Plant》2023年第3期616-631,共16页Qian Liu Chenglu Zhao Kai Sun Yinlu Deng Zhenghe Li 
supported by grants from the National Key R&D Program of China(2022YFC2601000);the Natural Science Foundation of Zhejiang Province,China(no.LZ20C140004);the National Natural Science Foundation of China(no.31870142).
CRISPR/Cas genome-editing tools provide unprecedented opportunities for basic plant biology research and crop breeding.However,the lack of robust delivery methods has limited the widespread adoption of these revolutio...
关键词：genome editing CRISPR-Cas base editor RNA virus vector tomato spotted wilt virus BUNYAVIRUS delivery non-transgenic 
Transcriptome profiling highlights regulated biological processes and type III interferon antiviral responses upon Crimean-Congo hemorrhagic fever virus infection
《Virologica Sinica》2023年第1期34-46,共13页Qiong Mo Kuan Feng Shiyu Dai Qiaoli Wu Zhong Zhang Ashaq Ali Fei Deng Hualin Wang Yun-Jia Ning 
supported by the National Key Research and Development Program of China(2018YFA0507202);the National Natural Science Foundation of China(32170171,31870162,and 82161138003);the Youth Innovation Promotion Association of Chinese Academy of Sciences.
Crimean-Congo hemorrhagic fever virus(CCHFV)is a biosafety level-4(BSL-4)pathogen that causes Crimean-Congo hemorrhagic fever(CCHF)characterized by hemorrhagic manifestation,multiple organ failure and high mortality r...
关键词：Crimean-Congo hemorrhagic fever virus(CCHFV) Biosafety level-4(BSL-4)pathogen BUNYAVIRUS Transcriptome Type III interferon ER stress Virus-host interaction Antiviral therapeutics 
Discovery of a widespread presence bunyavirus that may have symbiont-like relationships with different species of aphids被引量：2
《Insect Science》2022年第4期1120-1134,共15页Xin An Wei Zhang Chao Ye Guy Smagghe Jin-Jun Wang Jinzhi Niu 
This research was supported by National Natural Sci-ence Foundation(32072423);National Natural Science Foundation of China-Major International(Regional)Joint Research Project(32020103010);111 Project(B18044);the Foundation Project of Southwest University(SWU019033).We thank Dr Bi-Yue Ding(Academy of Agricultural Sciences.Southwest Univer-sity)for the technical assistance in western bloting.The Ap-Uny colony and Ap-Efr colony were kindly pro-vided by Professors Tong-Xian Liu and Giuy Smagghe,respectively.
Aphids are important agricultural pests,vectors of many plant viruses and have sophisticated relationships with symbiotic microorganisms.Abundant asymptomatic RNA viruses have been reported in aphids due to the applic...
关键词：insec-specific virus pea aphid Phasmaviridae RNA virus RNAi 
Cryo-EM structure of glycoprotein C from Crimean-Congo hemorrhagic fever virus被引量：2
《Virologica Sinica》2022年第1期127-137,共11页Na Li Guibo Rao Zhiqiang Li Jiayi Yin Tingting Chong Kexing Tian Yan Fu Sheng Cao 
supported by the National Natural Science Foundation of China(31570161)
Crimean-Congo hemorrhagic fever virus(CCHFV)is a causative agent of serious hemorrhagic diseases in humans with high mortality rates.CCHFV glycoprotein Gc plays critical roles in mediating virus-host membrane fusion a...
关键词：Crimean-Congo hemorrhagic Fever virus(CCHFV) Glycoprotein C Fusion protein BUNYAVIRUS 
Establishment of a Reverse Genetic System of Severe Fever with Thrombocytopenia Syndrome Virus Based on a C4 Strain被引量：6
《Virologica Sinica》2021年第5期958-967,共10页Mingyue Xu Bo Wang Fei Deng Hualin Wang Manli Wang Zhihong Hu Jia Liu 
supported by grants from the National Natural Science Foundation of China(No.31900146;Open Research Fund Program of the State Key Laboratory of Virology of China(No.2020IOV003);Team project of Health Commission of Hubei Province(WJ2019C003)。
Severe fever with thrombocytopenia syndrome virus(SFTSV)is an emerging tick-borne bunyavirus that causes hemorrhagic fever-like disease(SFTS)in humans with a case fatality rate up to 30%.To date,the molecular biology ...
关键词：BUNYAVIRUS Severe fever with thrombocytopenia syndrome virus(SFTSV) MINIGENOME Reverse genetic system T7 polymerase C4 strain 
A Bunyavirus-Inducible Ubiquitin Ligase Targets RNA Polymerase IV for Degradation during Viral Pathogenesis in Rice被引量：9
《Molecular Plant》2020年第6期836-850,共15页Chao Zhang Ying Wei Le Xu Kang-Cheng Wu Liang Yang Chao-Nan Shi Guo-Yi Yang Dong Chen Fei-Fei Yu Qi Xie Shou-Wei Ding Jian-Guo Wu 
This work was supported by the National Natural Science Foundation of China(no.31772128,31722045,U1905203,and 31701757);the Fok Ying Tung Education Foundation(161024).
The ubiquitin-proteasome system(UPS)is an important post-translational regulatory mechanism that controls many cellular functions in eukaryotes.Here,we show that stable expression of P3 protein encoded by Rice grassy ...
关键词：ubiquitin-proteasome system NRPD1 Rice grassy stunt virus E3 ligase 
Type Ⅰ interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential
《Zoological Research》2018年第1期3-14,共12页Gary Wong Xiang-Guo Qiu 
supported by the National Natural Science Foundation of China International Cooperation and Exchange Program(8161101193);the National Science and Technology Major Project(2016ZX10004222)to G.Wong
Due to their inability to generate a complete immune response, mice knockout for type I interferon （IFN） receptors （Ifnar-/-） are more susceptible to viral infections, and are thus commonly used for pathogenesis s...
关键词：Ifnar Mice Animal model FLAVIVIRUS FILOVIRUS ARENAVIRUS BUNYAVIRUS Henipavirus Togavirus 
Entry of severe fever with thrombocytopenia syndrome virus被引量：9
《Virologica Sinica》2017年第1期44-50,共7页Fei Yuan Aihua Zheng 
funded by the National Key Plan for Scientific Research and Development of China (2016YFD0500300);the Strategic Priority Research Program of the Chinese Academy of Sciences (CAS) (XDB11030800);the Natural Science Foundation of China (L1524009)
Severe fever with thrombocytopenia syndrome virus （SFTSV） is a globe-shaped virus covered by a dense icosahedral array of glycoproteins Gn/Gc that mediate the attachment of the virus to host cells and the fusion of ...
关键词：severe fever with thrombocytopenia syndrome virus （SFTSV） BUNYAVIRUS ENTRY FUSION RECEPTOR 
Isolation,characterization,and phylogenic analysis of three new severe fever with thrombocytopenia syndrome bunyavirus strains derived from Hubei Province,China被引量：22
《Virologica Sinica》2017年第1期89-96,共8页Yanfang Zhang Shu Shen Junming Shi Zhengyuan Su Mingyue Li Wenjing Zhang Mengmeng Li Zhihong Hu Cheng Peng Xin Zheng Fei Deng 
supported by the Science and Technology Basic Work Program (2013FY113500);the National Key Research and Development Program (2016YFE 0113500) from the Ministry of Science and Technology of China;the European Union’s Horizon 2020 EVAg project (No 653316)
Hubei Province is a major epidemic area of severe fever with thrombocytopenia syndrome bunyavirus(SFTSV) in China. However, to date, a few SFTSV strains have been isolated from Hubei Province, preventing effective stu...
关键词：BUNYAVIRUS severe fever with thrombocytopenia syndrome bunyavirus （SFTSV） ISOLATION phylogenetic analysis GENOTYPE 
An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV被引量：33
《Science China(Life Sciences)》2013年第8期697-700,共4页ZHANG XiaoShuang LIU Yan ZHAO Li LI Bing YU Hao WEN HongLing YU Xue-Jie 
Severe fever with thrombocytopenia syndrome(SFTS) is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus,SFTSV,named after the disease.The transmission vectors and animal hosts of S...
关键词：SFTSV TICK THROMBOCYTOPENIA LEUKOPENIA BUNYAVIRUS PHLEBOVIRUS hemorrhagic fever emerging infectious diseases 
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