FLAVIVIRUS

作品数：55被引量：105H指数：5
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Pathogenesis and clinical management of arboviral diseases
《World Journal of Virology》2025年第1期9-50,共42页Victoria Cenci Dietrich Juan Marcos Caram Costa Marina Maria Gomes Leite Oliveira Carlos Eduardo Oliveira Aguiar Luis Guilherme de Oliveira Silva Marcel Silva Luz Fabian Fellipe Bueno Lemos Fabrício Freire de Melo 
Supported by the Permanecer Program(part of the actions of the Office of Affirmative Actions);Education and Diversity of the Dean of Student Assistance at the Federal University of Bahia(UFBA);and CNPq Research Productivity Fellow.
Arboviral diseases are viral infections transmitted to humans through the bites of arthropods,such as mosquitoes,often causing a variety of pathologies associated with high levels of morbidity and mortality.Over the p...
关键词：ARBOVIRUSES Arbovirus infections DENGUE Zika virus Yellow fever Chikungunya virus Clinical diagnosis PATHOGENESIS FLAVIVIRUS Togaviridae infections 
Bibliometric analysis of flavivirus-host interactions and immune responses:Research hotspots and trends
《Biosafety and Health》2025年第1期38-43,共6页Yuxin Xiong Wenxin Fan Ying Wu 
supported by the National Key Research and Development Plan of China(2021YFC2300200);the National Natural Science Foundation of China(32122008).
Flaviviruses are zoonotic pathogens transmitted by infected mosquitoes and ticks,posing a persistent threat to global health.These infections lead to a diverse spectrum of diseases,broadly classified into two phenotyp...
关键词：Academic visualization BIBLIOMETRICS FLAVIVIRUS Immuneresponses 
Bis-benzylisoquinoline alkaloids inhibit flavivirus entry and replication by compromising endolysosomal trafficking and autophagy
《Virologica Sinica》2024年第6期892-908,共17页Lihong Huang Lele Liu Junhai Zhu Nanjun Chen Jie Chen Chuen-Fuk Chan Fei Gao Youqin Yin Jiufeng Sun Rongxin Zhang Kehui Zhang Wenbao Qi Jianbo Yue 
supported by the National Key Research and Development Program of China(2022YFD1800100);the National Natural Science Foundation of China(32302843,32070702,and 82161128014);GuangDong Basic and Applied Basic Research Foundation(2023A1515010748);Innovation and Technology Fund of Hong Kong(MRP/064/21,GHP/097/20GD,and MHP/072/21);Hong Kong Research Grant Council(RGC)grant(11103620 and 11104422);research grants from Shenzhen Science and Technology Innovation Committee(SGDX20201103093201010 and JCYJ20210324134007020);Kunshan Shuang Chuang Grant(kssc202302073);the Kunshan Municipal Government research funding。
Flaviviruses,such as dengue virus(DENV),Zika virus(ZIKV),and Japanese encephalitis virus(JEV),represent a substantial public health challenge as there are currently no approved treatments available.Here,we investigate...
关键词：Bis-benzylisoquinoline alkaloids(BBAs) FLAVIVIRUS Zika virus(ZIKV) Endolysosomes TRPML channels AUTOPHAGY 
A comprehensive overview on antiviral effects of baicalein and its glucuronide derivative baicalin
《Journal of Integrative Medicine》2024年第6期621-636,共16页Xin-yang Liu Wei Xie He-yang Zhou Hui-qing Zhang Yong-sheng Jin 
supported by National Natural Science Foundation of China(No.81573585);the Innovative Practice of Undergraduate Project of Naval Medical University(No.FH2021104)。
Natural product-based antiviral candidates have received significant attention.However,there is a lack of sufficient research in the field of antivirals to effectively combat patterns of drug resistance.Baicalein and ...
关键词：BAICALIN BAICALEIN Antiviral effects Influenza virus FLAVIVIRUS Hepatitis B virus Mechanism 
Viral-host molecular interactions and metabolic modulation:Strategies to inhibit flaviviruses pathogenesis
《World Journal of Virology》2024年第4期41-50,共10页Zeeshan Ahmad Khan Mukesh Kumar Yadav Dong-Woo Lim Hojun Kim Jing-Hua Wang AbuZar Ansari 
Supported by The South Korea Health Technology R and D Project through the South Korea Health Industry Development Institute,Funded by the Ministry of Health and Welfare,South Korea,No.HF20C0020.
Flaviviruses,which include globally impactful pathogens,such as West Nile virus,yellow fever virus,Zika virus,Japanese encephalitis virus,and dengue virus,contribute significantly to human infections.Despite the ongoi...
关键词：FLAVIVIRUS Nonstructural proteins Virus-host interaction Metabolism Inhibitors Vaccines 
Single-cell RNA sequencing to understand host-virus interactions
《Virologica Sinica》2024年第1期1-8,共8页Jia-Tong Chang Li-Bo Liu Pei-Gang Wang Jing An 
supported by the National Key Research and Devel-opment Program of China(2021YFC2300202);the National Natural Science Foundation of China(U1902210,81871641,81972979,82172266,82241071,and 81902048);the Support Project of High-level Teachers in Beijing Municipal Universities in the Period of 13th Five-year Plan(IDHT20190510);the Beijing Key Laboratory of Emerging In-fectious Diseases(DTKF202103).
Single-cell RNA sequencing(scRNA-seq)has allowed for the profiling of host and virus transcripts and host-virus interactions at single-cell resolution.This review summarizes the existing scRNA-seq technologies togethe...
关键词：Single-cell RNA sequencing(scRNA-seq) Host-virus interaction COVID-19 FLAVIVIRUS 
Resveratrol as an epigenetic therapy for flavivirus infection:A narrative review
《Asian Pacific Journal of Tropical Medicine》2023年第12期546-557,I0001-I0013,共25页Kim-Ling Chin Kim-Kee Tan Sazaly Abu Bakar Nurhafiza Zainal 
funding from the Ministry of Higher Education,Malaysia for niche area research under the Higher Institution Centre of Excellence(HICoE)program(MO002-2019&TIDREC-2023).
Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide.Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrh...
关键词：Infectious diseases Epigenetic RESVERATROL FLAVIVIRUS DNA methylation HISTONE Non-histone proteins MICRO-RNA 
Flavivirus-infected hosts attract more mosquitoes to bite
《Frontiers of Medicine》2023年第2期355-357,共3页Hong Zhang Xi Yu Yibin Zhu Gong Cheng 
Mosquitoes adapt to different habitats and feed on a variety of animals.Anthropophilic female mosquitoes,such as Aedes aegypti and Anopheles gambiae,have a strong innate drive to detect their human hosts and acquire b...
关键词：diseases INFECTED YELLOW 
Contribution of phylogenetics to understanding the evolution and epidemiology of dengue virus被引量：1
《Animal Models and Experimental Medicine》2022年第5期410-417,共8页Xi Yu Gong Cheng 
National Key Research and Development Plan of China,Grant/Award Number:2018YFA0507202,2020YFC1200100 and 2021YFC2300200;National Natural Science Foundation of China,Grant/Award Number:31825001,32188101,81730063,81961160737 and 82102389;Provincial Innovation Team for the Prevention and Control of Highly Pathogenic Pathogens,Institute of Medical Biology,Chinese Academy of Medical Sciences,Grant/Award Number:202105AE160020;Shenzhen San-Ming Project for Prevention and Research on Vector-borne Diseases,Grant/Award Number:SZSM201611064;Shenzhen Science and Technology Project,Grant/Award Number:JSGG20191129144225464;Tsinghua University Spring Breeze Fund,Grant/Award Number:2020Z99CFG017;Young Elite Scientists Sponsorship Program,Grant/Award Number:2021QNRC001;Yunnan Cheng Gong Expert Work-Station,Grant/Award Number:202005AF150034。
Dengue virus(DENV)is one of the most important arboviral pathogens in the tropics and subtropics,and nearly one-third of the world's population is at risk of infection.The transmission of DENV involves a sylvatic cycl...
关键词：dengue virus(DENV) EVOLUTION FLAVIVIRUS PHYLOGENETICS 
In vitro and in vivo characterization of erythrosin B and derivatives against Zika virus被引量：1
《Acta Pharmaceutica Sinica B》2022年第4期1662-1670,共9页Zhong Li Jimin Xu Yuekun Lang Xiangmeng Wu Saiyang Hu Subodh Kumar Samrat Anil M.Tharappel Lili Kuo David Butler Yongcheng Song Qing-Yu Zhang Jia Zhou Hongmin Li 
This study was partially supported by grants AI131669,AI140726,and AI141178 from the National Institute of Allergy and Infectious Diseases(NIAID,USA);the National Institutes of Health(Hongmin Li and Jia Zhou);Additionally,Jia Zhou is partly supported by the John D.Stobo,M.D.Distinguished Chair Endowment Fund at UTMB;Hongmin Li is additionally supported by NIH grants AI133219,AI134568,AI140406,and AI140491,USA;the R.Ken and Donna Coit Endowed Chair fund in Drug Discovery.
Zika virus(ZIKV)causes significant human diseases without specific therapy.Previously we found erythrosin B,an FDA-approved food additive,inhibited viral NS2B−NS3 interactions,leading to inhibition of ZIKV infection i...
关键词：FLAVIVIRUS Zika virus Dengue virus ANTIVIRAL Protease inhibitor Erythrosin B 
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