云南高校图书馆联盟文献共享服务平台- HISTONE

HISTONE: 作品数：283被引量：1002H指数：15; 导出分析报告; 相关作者：孙树汉杨富刘耘王朝晖张红更多>>; 相关机构：中国科学院第二军医大学哈尔滨工业大学中国医学科学院北京协和医学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

The Role of Linker Histone Mutation in Oncogenesis: Molecular Mechanism and Structural Impact: 《BIOCELL》2025年第4期519-538,共20页Gege Liu Houfang Zhang Yunhui Peng; supported by the National Natural Science Foundation of China(No.12205112);financially supported by self-determined research funds of CCNU from the colleges’basic research and operation of MOE(CCNU24JC012);supported by Natural Science Foundation of Wuhan(No.2024040801020302).; Nucleosomes play a vital role in chromatin organization and gene regulation,acting as key hubs that inter-act with various chromatin-associated factors through diverse binding mechanisms.Recent research has highlighte...; 关键词：Linker histone H1 EPIGENETICS histone cancer mutations chromatin structure NUCLEOSOME

ACSS2:Tumor-promoting lactyl-CoA synthetase that drives histone lactylation: 《hLife》2025年第3期118-120,共3页Katherine L.Wang Zhongsheng You; Lactate,a product of aerobic glycolysis,is frequently elevated in tumor cells due to the Warburg effect and frequent hypoxia[1].This functionally versatile molecule not only serves as a critical energy source and a bu...; 关键词：ELEVATED frequent VERSATILE

ALFIN-like proteins link histone H3K4me3 to H2A ubiquitination and coordinate diverse chromatin modifications in Arabidopsis: 《Molecular Plant》2025年第1期130-150,共21页Xiao-Min Su Dan-Yang Yuan Na Liu Zhao-Chen Zhang Minqi Yang Lin Li She Chen Yue Zhou Xin-Jian He; supported by the National Natural Science Foundation of China to X.-J.H.(grant numbers 32025003 and 32470628).; Trimethylation of histone H3K4(H3K4me3)is widely distributed at numerous actively transcribed protein-coding genes throughout the genome.However,the interplay between H3K4me3 and other chromatin modifications in plant...; 关键词：ALFIN-like proteins PRC1 HISTONE H3K4me3 H2Aub H2A.Z

Histone H4K8hib modification promotes gene expression and regulates rice immunity: 《Molecular Plant》2025年第1期9-13,共5页Qiutao Xu Xuan Ma Xuelu Wei Zhengting Chen Yuhang Duan Yuliang Ju Zhaoyun Wang Jing Chen Lu Zheng Xiaolin Chen Junbin Huang Jisen Zhang Xiaoyang Chen; funded by the National Natural Science Foundation of China(32100465 and 32302302);the Key Research and Development Program of Anhui Province(202204c06020028);the Starting Research Grant for High-level Talents from Guangxi University(ZX01080033124005);the Scientific Research and Development Fund of the College of Agriculture,GuangxiUniversity(EE101761).; Dear Editor,Histones undergo various post-translational modifications essential for transcription,DNA replication,repair,and other cellular processes(Li et al.,2018).While histone methylation and acetylation are well ...; 关键词：IMMUNITY MODIFICATION EXPANDING

A programmable CRISPR/dCas9-based epigenetic editing system enabling loci-targeted histone citrullination and precise transcription regulation: 《Journal of Genetics and Genomics》2024年第12期1485-1493,共9页Xiaoya Zhang Abhisek Bhattacharya Chunxiang Pu Yan Dai Jia Liu Lang Rao Chaoguang Tian; funded by the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-CXRC-048)。; Histone citrullination,an important post-translational modification mediated by peptidyl arginine deiminases,is essential for many physiological processes and epigenetic regulation.However,the causal relationship betw...; 关键词：HISTONE CITRULLINATION Epigenetic editor Peptidyl arginine deiminase dCas9

The walnut-derived peptide TW-7 improves mouse parthenogenetic embryo development of vitrified MII oo ytes potentially by promoting histone lactylation: 《Journal of Animal Science and Biotechnology》2024年第6期2333-2350,共18页Yaozong Wei Bo Pan Jianpeng Qin Beijia Cao Tianyi Lv Jiangfeng Ye Ao Ning Kunlin Du Xiangyi Chen Shuqi Zou Shengqin Zang Guozhi Yu Tianzeng Song Qiuxia Liang Guangbin Zhou; supported by the National Key Research and Development Program of China(No.2021YFD1200403);the National Natural Science Foundation of China(No.32072735);Xigaze City regional Science and technology Collaborative innovation project-Genetic resources of rescue protection for Zhangmu goat(No.QYXTZX-RKZ2023-06)。; Background Previous studies have shown that the vitrification of metaphaseⅡ(MⅡ)oocytes significantly represses their developmental potential.Abnormally increased oxidative stress is the probable factor;however,the u...; 关键词：Histone lactylation OOCYTE TW-7 VITRIFICATION Zygotic genome activation

Targeting SRSF10 might inhibit M2 macrophage polarization and potentiate anti-PD-1 therapy in hepatocellular carcinoma: 《Cancer Communications》2024年第11期1231-1260,共30页Jialiang Cai Lina Song Feng Zhang Suiyi WuGuiqi Zhu Peiling Zhang Shiping Chen Junxian Du Biao Wang Yufan Cai Yi Yang Jinglei Wan Jian Zhou Jia Fan Zhi Dai; supported by the National Natural Science Foundation of China(No.82372946 and No.82072670);the 12 Leading Project of the Science and Technology Committee of Shanghai Municipality(No.21Y21900100);the Project of Shanghai Municipal Health Commission(No.202140269).; Background:The efficacy of immune checkpoint blockade therapy in patients with hepatocellular carcinoma(HCC)remains poor.Although serine-and arginine-rich splicing factor(SRSF)family members play crucial roles in tumo...; 关键词：GLYCOLYSIS Histone lactylation Immune checkpoint blockade Serine and arginine rich splicing factor 10 Tumor-Associated Macrophage

Virome-wide analysis of histone modification mimicry motifs carried by viral proteins: 《Virologica Sinica》2024年第5期793-801,共9页Yang Xiao Shuofeng Yuan Ye Qiu Xing-Yi Ge; funded by the National Natural Science Foundation of China(No.U2002218,32270170 and 81902070);the Fund of Hunan University(521119400156);the Science and Technology Innovation Program of Hunan Province(2024RC1028).; Histone mimicry(HM)refers to the presence of short linear motifs in viral proteins that mimic critical regions of host histone proteins.These motifs have the potential to interfere with host cell epigenome and counter...; 关键词：Histone mimicry Viral proteins Histone modification EVOLUTION CORONAVIRUS

Facile semisynthesis of histone H3 enables nucleosome probes for investigation of histone H_(3)K79 modifications: 《Chinese Chemical Letters》2024年第10期321-324,共4页Kun Zou Yihang Xiao jinyu Yang Mingxuan Wu; support from National Natural Science Foundation of China(Nos.22077103 and 22161132006);Westlake University startup。; Histone H3K79 modifications are essential to regulate chromatin structure and gene transcription,but understanding of the molecular mechanisms is limited.Because H3K79 is at globular domain,short histone peptide canno...; 关键词：HISTONE H3K79 modifications METHYLATION SUCCINYLATION SEMISYNTHESIS Nucleosome probes

The PRR-EC complex and SWR1 chromatin remodeling complex function cooperatively to repress nighttime hypocotyl elongation by modulating PIF4 expression in Arabidopsis: 《Plant Communications》2024年第9期184-199,共16页Jin Hoon Won Jeonghyang Park Hong Gil Lee Sangrae Shim Hongwoo Lee Eunkyoo Oh Pil Joon Seo; supported by the Basic Science Research(NRF2022R1A2B5B02001266 to P.J.S.and NRF-2023R1A2C3002386 to E.O.);Basic Research Laboratory(NRF-2022R1A4A3024451)programs provided by the National Research Foundation of Korea.; The circadian clock entrained by environmental light-dark cycles enables plants to fine-tune diurnal growth and developmental responses.Here,we show that physical interactions among evening clock components,including ...; 关键词：hypocotyl elongation circadian clock PRR Evening Complex histone H2A.Z SWR1 complex

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