Histone H4K8hib modification promotes gene expression and regulates rice immunity  

作　　者：Qiutao Xu Xuan Ma Xuelu Wei Zhengting Chen Yuhang Duan Yuliang Ju Zhaoyun Wang Jing Chen Lu Zheng Xiaolin Chen Junbin Huang Jisen Zhang Xiaoyang Chen 

机构地区：[1]State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources,College of Agriculture,Guangxi University,Nanning 530004,China [2]College of Agriculture,Ningxia University,Yinchuan 750021,China [3]National Key Laboratory of Crop Genetic Improvement,Huazhong Agricultural University,Wuhan 430070,China [4]State Key Laboratory of Agricultural Microbiology,Huazhong Agricultural University,Wuhan 430070,China [5]Anhui Province Key Laboratory of Crop Integrated Pest Management,Anhui Agricultural University,Hefei 230036,China

出　　处：《Molecular Plant》2025年第1期9-13,共5页分子植物(英文版)

基　　金：funded by the National Natural Science Foundation of China(32100465 and 32302302);the Key Research and Development Program of Anhui Province(202204c06020028);the Starting Research Grant for High-level Talents from Guangxi University(ZX01080033124005);the Scientific Research and Development Fund of the College of Agriculture,GuangxiUniversity(EE101761).

摘　　要：Dear Editor,Histones undergo various post-translational modifications essential for transcription,DNA replication,repair,and other cellular processes(Li et al.,2018).While histone methylation and acetylation are well studied,emerging short-chain lysine acylations,such as crotonylation,succinylation,lactylation,acetoacetylation,and 2-hydroxyisobutyrylation(Khib)(Li et al.,2018;Lu et al.,2018;Zheng et al.,2021;Gao et al.,2023),are expanding the field of epigenetic regulation.Of these short-chain acylations,Khib has garnered recent attention as an evolutionarily conserved modification on histone proteins,extensively characterized in yeast and animals,where it plays a role in glucose response and virus infection(Huang et al.,2017;Zhao et al.,2022).In plants,H4K8hib has been identified on histones,but its functions and the enzymes involved in its removal remain unclear.In this study,we analyzed the H4K8hib modification profile in rice,exploring its role in the rice immune response and identifying the enzymes responsible for its removal.

关 键 词：IMMUNITY MODIFICATION EXPANDING 

分 类 号：S51[农业科学—作物学]