云南高校图书馆联盟文献共享服务平台- NUCLEOSOME

NUCLEOSOME: 作品数：58被引量：101H指数：5; 导出分析报告; 相关领域：生物学更多>>; 相关作者：孙啸刘宏德黄焕聂玉敏侯越更多>>; 相关机构：东南大学内蒙古科技大学内蒙古大学河北联合大学更多>>; 相关期刊：《Signal Transduction and Targeted Therapy》《Frontiers of Information Technology & Electronic Engineering》《Science China(Life Sciences)》《Frontiers in Biology》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市青年科技启明星计划更多>>

The Role of Linker Histone Mutation in Oncogenesis: Molecular Mechanism and Structural Impact: 《BIOCELL》2025年第4期519-538,共20页Gege Liu Houfang Zhang Yunhui Peng; supported by the National Natural Science Foundation of China(No.12205112);financially supported by self-determined research funds of CCNU from the colleges’basic research and operation of MOE(CCNU24JC012);supported by Natural Science Foundation of Wuhan(No.2024040801020302).; Nucleosomes play a vital role in chromatin organization and gene regulation,acting as key hubs that inter-act with various chromatin-associated factors through diverse binding mechanisms.Recent research has highlighte...; 关键词：Linker histone H1 EPIGENETICS histone cancer mutations chromatin structure NUCLEOSOME

Facile semisynthesis of histone H3 enables nucleosome probes for investigation of histone H_(3)K79 modifications: 《Chinese Chemical Letters》2024年第10期321-324,共4页Kun Zou Yihang Xiao jinyu Yang Mingxuan Wu; support from National Natural Science Foundation of China(Nos.22077103 and 22161132006);Westlake University startup。; Histone H3K79 modifications are essential to regulate chromatin structure and gene transcription,but understanding of the molecular mechanisms is limited.Because H3K79 is at globular domain,short histone peptide canno...; 关键词：HISTONE H3K79 modifications METHYLATION SUCCINYLATION SEMISYNTHESIS Nucleosome probes

Illuminating nucleosome interactions: 《Cell Research》2024年第10期671-672,共2页Silvija Bilokapic Mario Halic; In a recent article published in Cell Research,the structure of an array of 12 nucleosomes compacted to a 30-nm fiber reveals details about nucleosome-nucleosome interactions and the binding and folding of linker hist...; 关键词：NUCLEOSOME INTERACTIONS STRING

Structural basis for linker histone H5-nucleosome binding and chromatin fiber compaction: 《Cell Research》2024年第10期707-724,共18页Wenyan Li Jie Hu Feng Song Juan Yu Xin Peng Shuming Zhang Lin Wang Mingli Hu Jia-Cheng Liu Yu Wei Xue Xiao Yan Li Dongyu Li Hui Wang Bing-Rui Zhou Linchang Dai Zongjun Mou Min Zhou Haonan Zhang Zheng Zhou Huidong Zhang Yawen Bai Jin-Qiu Zhou Wei Li Guohong Li Ping Zhu; supported by grants from the Ministry of Science and Technology of China(2023YFA0913400 to P.Z.and G.L.,and 2021YFA1300100 to P.Z.);the National Natural Science Foundation of China(31991161 and 32230020 to G.L.,32241029 and 31730023 to P.Z.,and 31500606 and 62131004 to F.S.);the Chinese Academy of Sciences Strategic Priority Research Program(XDB37010100 to P.Z.);supported by the Beijing Municipal Science and Technology Committee(Z221100007022001);the Fundamental Research Funds for the Central Universities(2042022dx0003);HHMI international research scholar grant(55008737)to G.L.;Taishan Young Scholars Program of Shandong Province(TSQN20161049)to F.S.Y.B.;B.Z.are supported by the intramural research program of the National Cancer Institute,National Institutes of Health,USA.; The hierarchical packaging of chromatin fibers plays a critical role in gene regulation.The 30-nm chromatin fibers,a central-level structure bridging nucleosomal arrays to higher-order organizations,function as the fi...; 关键词：chromato fibers polarity

Studying large biomolecules as sedimented solutes with solid-state NMR: 《Biophysics Reports》2024年第4期201-212,共12页Fan Shi Tong Zhang Juan Li Chaowei Shi Shengqi Xiang; supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB 37040200);CAS Project for Young Scientists in Basic Research(YSBR-068).; Sedimentation solid-state NMR is a novel method for sample preparation in solid-state NMR(ssNMR)studies.It involves the sedimentation of soluble macromolecules such as large protein complexes.By utilizing ultra-high c...; 关键词：Sedimentation NMR Solid-state NMR ULTRACENTRIFUGATION Magic angle spinning NUCLEOSOME

Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2被引量：1: 《Science China(Life Sciences)》2024年第6期1305-1307,共3页Songlin Gan Wen-Si Yang Liting Wei Zhiguo Zhang Rui-Ming Xu; supported by the National Key Research and Development Program of China(2019YFA0508900);the National Natural Science Foundation of China(32330021,31991162,32200477);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB37010100)。; Dear Editor,The passage of DNA replication forks during eukaryotic cell division disrupts the nucleosomes they encounter,and de novo assembly of nucleosomes onto replicated DNA must take place to restore chromatin str...; 关键词：STRUCTURE NUCLEOSOME passage

PEGA:probabilistic environmental gradient-driven genetic algorithm considering epigenetic traits to balance global and local optimizations: 《Frontiers of Information Technology & Electronic Engineering》2024年第6期839-855,共17页Zhiyu DUAN Shunkun YANG Qi SHAO Minghao YANG; Project supported by the National Natural Science Foundation of China(No.61672080)。; Epigenetics’flexibility in terms of finer manipulation of genes renders unprecedented levels of refined and diverse evolutionary mechanisms possible.From the epigenetic perspective,the main limitations to improving t...; 关键词：Evolutionary algorithm EPIGENETICS Epigenetic algorithm Probabilistic environmental vector Variable nucleosome reorganization

Rpd3S meets the nucleosome: 《Cell Research》2024年第1期1-2,共2页Michael J.Carrozza Jerry L.Workman; Two recent reports in Cell Research present cryo-electron microscopy structures of the Rpd3S HDAC complex bound to the nucleosome.These structures provide novel insight into the binding properties of the Rpd3S subunit...; 关键词：INSIGHT PROPERTIES MODIFIED

Do plant histone variants stand idly by while DNA viruses invade the nucleus?: 《Stress Biology》2023年第1期507-510,共4页Zhihao Jiang Rosa Lozano-Durán; the recipient of Walter Benjamin Programme from the DFG(grant N.511563636).; Main text,In the eukaryotic nucleus,the cellular DNA is always wrapped around protein octamers containing two molecules each of histone H2A,H2B,H3,and H4,forming the nucleosome to compact,protect,organize,and control ...; 关键词：DNA NUCLEOSOME PLANT

Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme: 《Cell Research》2023年第12期971-974,共4页Yueyue Zhang Mengxue Xu Po Wang Jiahui Zhou Guangxian Wang Shuailong Han Gang Cai Xuejuan Wang; This study was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB37010000);the National Natural Science Foundation of China(31922035,32030057,31890783,and32271255);the Fundamental Research Funds for the Central Universities(WK9100000032 and YD2070002012).; Dear Editor,Histone deacetylases(HDACs)are evolutionally conserved enzymes that remove acetyl modifications from histones and play a central role in epigenetic gene silencing.1 Class I HDACs are promising targets for ...; 关键词：NUCLEOSOME CATALYSIS REMOVE

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