118例乳腺肿块细胞块活检、细胞涂片和术后病理诊断对比分析  

Comparative analysis of fine-needle aspiration cell block biopsy,cells smear and postoperative pathological diagnosis in 118 patients with breast lumps

作　　者：卞铁荣[1] 邢宏运[1] 唐利[1] 李燕[1] 陈庄[1] 吴云飞[1] 

机构地区：[1]四川泸州医学院附属医院,四川泸州646000

出　　处：《中国卫生检验杂志》2013年第7期1753-1754,共2页Chinese Journal of Health Laboratory Technology

基　　金：四川省重点学科重点建设项目资助(SZD0421)

摘　　要：目的:探讨针吸细胞块活检确诊乳腺肿块的诊断价值。方法:对118例乳腺肿块患者经针吸细胞涂片检查、针吸细胞块活检与术后组织学病理诊断对比分析。结果:针吸细胞块活检与针吸细胞学涂片的的诊断结果比较,前者的敏感性、特异性、总体诊断符合率、阴性准确率、阳性准确率均要高出后者,假阳性率及假阴性率亦低于后者。尤其阴性准确率,针吸细胞块活检为77.27%(17/22),针吸细胞学涂片为65.38%(17/26),高出近12%。结论:细胞块活检对乳腺癌肿块诊断有独特价值,该方法不仅快速、简便,较为准确,而且综合之相关诊断指标优于细胞涂片的结果,并能弥补细胞涂片对确定肿瘤来源及进一步分型的缺陷,为临床医生提供准确的诊疗方案,值得推广应用。Objective： To evaluate the diagnostic value of the fine - needle aspiration cell block： biopsy in breast lumps. Methods： One hundred and eighteen patients with breast lumps were examined by fine -needle aspiration cells smear, fine - needle aspiration cell block biopsy and postoperative histological pathology diagnosis, then the resuits were analyzed. Results： Compared with fine - needle aspiration cells smear, fine - needle aspiration cell block biopsy showed higher sensitivity, specificity, overall diagnostic coincidence rate, negative accuracy rate, positive accuracy rate, and lower false positive rate and false negative rate. Especially for the negative accuracy rate, fine - needle aspiration cell block biopsy was 77.27% （17/22）, while fine -needle aspiration cells smear was 65.38% （17/26）. Conclusion ： The results of comparative analysis suggested that fine - needle aspiration cell block biopsy had unique value for breast lumps. This method was not only fast, simple and relatively accurate, but also the related diagnosis indexes of fine -needle aspiration cell block biopsy were superior to the fine -needle aspiration cells smear. And the characteristics of fine - needle aspiration cell block biopsy in the initial diagnostic procedure can provide important reference for clinic doctors.

关 键 词：乳腺肿块 细胞块活检 组织学诊断 

分 类 号：R737.9[医药卫生—肿瘤]