军人失眠症患者探究性眼动与事件相关电位研究  

Investigation on exploratory eye movement and event related potentials in soldiers with insomnia

作　　者：梁学军 甘景梨 高存友 赵兰民 张夏莲 刘立志 

机构地区：[1]解放军第91中心医院全军精神疾病防治研究所,河南焦作454003

出　　处：《癫痫与神经电生理学杂志》2013年第4期205-207,共3页Journal of Epileptology and Electroneurophysiology(China)

摘　　要：目的：探讨探究性眼动（EEM）和事件相关电位（ERP）对军人失眠症患者认知功能评估的临床价值。方法：采用EEM和ERP对某三级甲等部队医院心理科收治的48例失眠症官兵（研究组）和随机抽取某部50名官兵（对照组）进行测定，并将结果进行比较。结果：①军人失眠症患者EEM凝视点数（NEF）、反应探索评分（RSS）及D值与对照组相比，差异有统计学意义（P〈0．01）；②军人失眠症患者ERP测定，N2、P3波潜伏期较对照组延长，P3波幅较对照组降低，两者比较差异均有显著性意义（P〈0．01）；③相关分析显示，研究组N2、P3波潜伏期与NEF、RSS呈负相关（r=-0．19～-0．42，P〈0．05或0．01），与D值呈正相关（r=0．30，0．48，P〈0．01）；P3波幅与NEF、RSS呈正相关（r=0．38，0．51，P〈0．01），与D值呈负相关（r=-0．32，P％0．01）。结论：EEM和ERP测定具有良好的一致性，可作为判断失眠症患者认知功能的重要指标。Objective.. To explore the clinical value of exploratory eye movement and event related potentials to recognition functional assessment of soldiers with insomnia. Methods： 48 soldiers with insomnia and 50 normal controls were measured with exploratory eye movement（EEM） and event related potentials （ERP）. Results：①Compared with the control group, the number of eye fixation（NEF） and responsive search score（RSS） in soldiers with insomnia were significantly lower, but D grade was higher （P〈0.01） . ② Compared with the control group, the latency period of N2 and P3 was prolonged, and the amplitude of P3 waves was degraded（P〈0.01）. ③ Correlation analysis showed that there were signiiicant negative correlation of N2 and P3 with NEF and RSS r=-0.19～-0.42, P〈0.05 or 0.01）, and direct correlation with D grade（r=0.30, 0.48, P〈0.01） in both the study group and the control group. The amplitude of P3 waves was directly related to NEF and RSS（r=0.38, 0.51, P〈0.01） ,and negative related to D grade（r= -0, 32, P〈0.01）. Conclusion：There is satisfactory concordance between EEM and ERP, which serve as an important index to judge cognitive function of insomnia.

关 键 词：军人 失眠症 探究性眼动 事件相关电位 凝似点数（NEF） 反应性探索评分（RSS） 

分 类 号：R749.69[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]