老年性白内障晶状体核硬度及相关因素研究  

The nuclear hardness and associated factors of age related cataract

作　　者：胡春玲 张晓农[2] 惠延年[3] 

机构地区：[1]甘肃省金昌市金川公司医院眼科,737103 [2]同济医科大学同济医院眼科 [3]第四军医大学西京医院眼科

出　　处：《中华眼科杂志》2000年第5期337-340,共4页Chinese Journal of Ophthalmology

摘　　要：目的　检测老年性白内障晶状体核硬度并探讨其相关的因素。方法　 5 0岁以上老年性白内障患者 47例 (4 7只眼 )。术前散瞳 ,并按LOCSⅡ分类。测量白内障囊外摘出晶状体核的重量、中心厚度和直径 ,采用测定穿透晶状体核力量的装置 ,测定晶状体核的硬度。多元回归分析晶状体核硬度与年龄、核颜色、病程等因素的关系。结果　切穿颜色为Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级核所需用的平均力分别为 (0 5 1± 0 2 9)、(1 41± 0 35 )、(1 95± 0 42 )、(2 96± 0 6 2 )N。最大力均位于核中心。回归分析 85 %老年性白内障患者核硬度可采用核颜色及混浊度衡量。皮质及后囊下混浊与核硬度无关。糖尿病及高度近视导致核硬度增加。核颜色与核重量 (r =0 45 6 5 )、直径 (r =0 5 2 6 3)、厚度(r=0 5 5 5 2 )呈正相关性 (P <0 0 0 1) ,而年龄与核重量有弱相关性 (r=0 32 3 9,P <0 0 5 )。结论　老年性白内障晶状体核颜色是判断核硬度、直径和厚度有意义的指标 。Objective To determine the nuclear hardness and associated factors of age related cataract Methods Forty seven eyes of 47 patients with age related cataract aged >50 years were studied The opacity of lenses was assessed and classified by the LOCS II pre operatively The lens nucleus obtained during extracapsular cataract extraction (ECCE) was measured By means of a fine conical probe and dynamometer, the resistance to penetration of different lens layers was transferred to an electric signal and recorded by a function recorder The hardness to the penetration of different lens layers was calculated Multivariate regression analysis was applied to the parameters including age, color of the nucleus, duration of symptoms and other factors Results The mean force required to penetrate the lens was (0 51±0 29) Newtons (N) for grade I, (1 41±0 35) N for grade II and (1 95±0 42) N for grade III; it increased to (2 96±0 62) N for grade IV The hardest part of the lens was located at the nucleus center Multivariate analysis of the data showed that 85% of the variation in hardness could be explained in terms of color and opacity The patients with myopia and diabetics had an increased incidence of grading IV nuclear sclerosis Regression analysis revealed a positive correlation between nucleus color and weight (r=0 456 5), diameter (r=0 526 3), thickness (r=0 555 2) and hardness (r=0 896 9),P<0 001 There was a weak positive correlation between age and the weight of nucleus (r=0 323 9, P<0 05) Conclusions The results indicate that the color can be used more reliably to predict physical characteristics of lens nucleus, the preoperative knowledge of which would help the surgeon in planning small incision surgery including phacoemulsification

关 键 词：白内障 晶体核 硬度 相关因素 老年人 

分 类 号：R776.1[医药卫生—眼科]