小肠间质瘤外科治疗后复发的危险因素  

Risk factors of recurrence on small intestinal stromal tumor after surgical treatment

作　　者：周卫华[1,2] 梁颖[3] 李明毅[1,2] 谭洁媚[1,2] 

机构地区：[1]广东省江门市中心医院 [2]中山大学附属江门医院,529030 [3]中山大学附属肿瘤医院,广州市510060

出　　处：《临床合理用药杂志》2013年第20期18-19,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨小肠间质瘤外科治疗后复发的危险因素。方法回顾性分析33例小肠间质瘤患者的病历资料,了解何种因素对复发产生重要影响。结果肿瘤最大径≥3cm(χ2=6.904,P=0.009)和高侵袭危险度(χ2=5.774,P=0.016)的患者术后复发率显著升高。复发肿瘤的切除率为57.9%(11/19),显著低于初治患者的手术切除率91.7%(33/36)(χ2=6.880,P=0.009)。结论小肠间质瘤的复发与肿瘤大小和侵袭危险度呈正相关。复发肿瘤手术切除率显著低于初治手术切除率,但术后再次复发率与初治手术的复发率相近。Objective To investigate the risk factors of recurrence on small intestinal stromal tumor after operation. Methods The clinical data of 33 cases with small intestinal stromal tumor were analyzed retrospectively. The possible risk factors leading to the recurrence were observed. The resectable rate and recurrent rate of recurrent cases were compared with the first-treated case. Results The tumors with biggest diameter≥3cm（ χ2 = 6. 904,P = 0. 009） and high invasive risk had higher recurrent rate（ χ2 = 5. 774,P = 0. 016） . The resectable rate of recurrent small intestinal stromal tumor was 57. 9% （ 11 / 19） ,which was significantly lower than that of first-treated ones 91. 7% （ 33 /36） （ χ2 = 6. 880,P = 0. 009） . Conclusion The size and invasive risk of tumor are positively proportional to the recurrent rate of small intestinal stromal tumor. The resectable rate of recurrent small intestinal stromal tumor is significantly lower than that of the first-treated ones,but recurrent rates are similar in the 2 groups.

关 键 词：胃肠间质瘤 复发 小肠肿瘤 外科手术 

分 类 号：R735.32[医药卫生—肿瘤]