HHV-8和HIV感染与卡波西肉瘤发病关系的研究进展  

Research development of HHV-8 and HIV infection for kaposi sarcoma odisease

作　　者：关灿彬[1,2] 普雄明[2] 李幸丽[1] 

机构地区：[1]石河子大学医学院,新疆石河子832002 [2]新疆维吾尔自治区人民医院皮肤科,乌鲁木齐830001

出　　处：《农垦医学》2013年第1期52-55,共4页Journal of Nongken Medicine

基　　金：新疆维吾尔自治区自然科学基金项目(2009211A24)

摘　　要：Kaposi肉瘤(Kaposi's Sarcoma,KS)是一种罕见的软组织恶性多发性色素性血管肉瘤,又称多发性、特发性出血性肉瘤。人类疱疹病毒8型(Human herpesvirus 8,HHV-8),又称为KS相关性疱疹病毒(KS-associated her-pesvirus,KSHV),目前研究表明,HHV-8与各型KS均有密切的联系,是各种临床类型KS发病的重要病原体。KS患者具有较高的病死率,特别是AIDS-KS型。随着AIDS发病率的逐年增长,HHV-8和HIV双重感染KS患病率也呈逐年增长趋势。Kaposi Sarcoma（ Kaposi＇s Sarcoma, KS）is a rare and soft tissue malignant multiple pigmentary angiosarco- ma,it is also called multiple, idiopathic hemorrhagic Sarcoma, Human herpesviras 8（ Human herpesvirus 8, HHV-8）and named KS correlation herpes virus too（ KS-associated herpesvirus, KSHV）. The present study showed that HHV-8 and each subject KS all have the close relation,which is all sorts of important pathogens resulted in all kinds of clinical type KS path- ogenetic. KS patients has high mortality,especially AIDS-KS type. With the AIDS incidence is increasing year by year,Prev- alence of HHV-8 and HIV superinfection KS was also increasing.

关 键 词：HHV-8 HIV KS 发病机制 

分 类 号：R739.5[医药卫生—肿瘤]