胡椒碱与胡椒酸甲酯降血脂作用对比研究  

Comparative study on the Hypolipidemic effect of piperine and methyl piperate from Piper longum's extract

作　　者：乌恩[1] 周昊霏[1] 韩松原[1] 

机构地区：[1]内蒙古医学院药学院无机化学教研室,内蒙古呼和浩特010059

出　　处：《西部医学》2013年第8期1146-1147,共2页Medical Journal of West China

摘　　要：目的荜茇提取物中胡椒碱与胡椒酸甲酯降血脂作用对比研究。方法通过荜茇提取胡椒碱,并将胡椒碱水解后制取胡椒酸甲酯。并将所得化合物进行了动物实验,以验证降血脂疗效。结果成功提取并合成了胡椒碱及胡椒酸甲酯,实验表明胡椒酸甲酯具有较好的降血脂作用。Objective To study the hypolipidemic effect of piperine and methyl piperate from Piper longum＇s ex- tract. Methods Piperine was extracted in Piper longum and methylpiperic acid was obtained by alkaline hydrolysis. Re- suits The piperine crystal and methylpiperic were obtained. Conclusion The hypolipidemic effect of methylpiperic pip- erate is better,

关 键 词：荜茇 胡椒碱 胡椒酸甲酯 降血脂 

分 类 号：R589.2[医药卫生—内分泌]