聚(乳酸-天冬氨酸)的合成及性能研究  

The Synthesis and Property Study of the Poly(Lactide-alt-Aspartic Acid)

作　　者：余飞[1] 刘文明[1] 

机构地区：[1]南昌大学应用化学研究所,江西南昌330031

出　　处：《塑料工业》2013年第8期7-11,共5页China Plastics Industry

基　　金：江西省科技厅科技支撑计划资助项目(2007ZD01900)

摘　　要：以天冬氨酸和氯乙酰氯为原料合成了3-[(苄氧羰基)-甲基]-吗啉-2,5-二酮,再与丙交酯共聚合成聚(乳酸-天冬氨酸),并用FTIR、1H NMR对其进行结构表征。研究了3-[(苄氧羰基)-甲基]-吗啉-2,5-二酮与丙交酯的共聚反应,探讨了不同催化剂用量、聚合时间、聚合温度对聚合物特性黏数的影响;并对共聚物与PLA的亲水性以及降解性能进行了对比。结果表明,催化剂用量为反应物质量的0.3%,聚合时间8 h,聚合温度160℃时,共聚物的特性黏数最大;改性后的聚乳酸亲水性能、降解性能都优于聚乳酸。3-[（benzyloxycarbonyl） methyl] morpholine-2,5-dione （MMD） was synthesized via aspartic acid and chloroacetyl chloride as the raw materials.Afterwards,poly（lactide-alt-aspartic acid） was obtained by copolymerizing lactide and MMD of which structure was confirmed by FTIR,1 H-NMR.Effects of catalyst amount,polymerization time and temperature on the inherent viscosity of the product were studied.In addition,the water absorption and degradation between this copolymer and PLA were investigated.It was revealed that at 160 ℃ for 8 h,with 0.3％ （wt） catalyst amount of the total reactants,co-polymer with the highest inherent viscosity can be achieved.The synthesized copolymer in this paper had improved water absorption and weight loss rate in comparison with PLA.

关 键 词：天冬氨酸 丙交酯 共聚物 

分 类 号：O631.3[理学—高分子化学]