牛奶和奶粉中维吉尼霉素残留量的液相色谱——串联质谱测定  

Determination of Virginiamycin Residue in Bovine Milk and Milk Powder by LC-MS-MS

作　　者：赵静[1] 李广仁[1] 乔德福[1] 苏海滨[1] 陶迎春[1] 杨晓旎[1] 张晨[1] 宋文斌[1] 

机构地区：[1]辽宁出入境检验检疫局辽检检疫处理实验室,辽宁大连116033

出　　处：《现代科学仪器》2013年第3期129-132,共4页Modern Scientific Instruments

摘　　要：建立了牛奶和奶粉中维吉尼霉素virginiamycin M1残留量的液相色谱——串联质谱测定方法。结果表明,维吉尼霉素M1在0.125μg/kg～8.00μg/kg范围内,具有良好的线性关系,相关系数r=0.9998。牛奶中维吉尼霉素M1方法检出限为0.25μg/kg,奶粉中维吉尼霉素M1方法检出限为2.00μg/kg。在4个添加水平上进行回收实验(n=10),牛奶平均回收率为62.04%～111.65%,相对标准偏差在8.455%～20.03%之间;奶粉平均回收率为85.49%～106.44%,相对标准偏差在2.467%～3.014%之间。The virginiamycin M1 residues in bovine milk and milk powder were determined with LC-MS-MS.This method solved the determination of virginiamycin M1 residues in bovine milk and milk powder.The calibration curve of cirginiamycin M1 showed good linearity in the range of 0.125μg/kg-8.00μg/kg with r=0.9998.The detection limit was 0.25μg/kg for bovine milk and 2.00μg/kg for milk powder.Spiked with standard at four levels（n=10）,the samples had the recoveries of 62.04%-111.65% for bovine milk and 85.49%-106.44% for milk powder, the relative standard deviation was 8.455%-20.03% for bovine milk and 2.467%-3.014% for milk powder.

关 键 词：维吉尼霉素 残留量 液相色谱-串联质谱 牛奶 奶粉 

分 类 号：TS252.7[轻工技术与工程—农产品加工及贮藏工程] O657.63[轻工技术与工程—食品科学与工程]