精神分裂症患者与分裂型人格个体的时间加工行为特点  

Behavioral performance of time processing in patients with schizophrenia and individuals with schizotypal personality features

作　　者：张琪[1,2] 王亚[1] 黄佳[1] 赵晴[1] 李占江[3] 陈楚侨[1] 

机构地区：[1]中国科学院心理研究所,神经心理学与应用认知神经科学,心理健康国家重点实验室,北京100101 [2]中国科学院大学,北京100040 [3]首都医科大学安定医院,北京100088

出　　处：《中国心理卫生杂志》2013年第7期544-549,共6页Chinese Mental Health Journal

基　　金：国家科技支撑计划项目(2012BAI36B01);中国科学院知识创新工程项目(KSCX2-EW-J-8);心理健康重点实验室资金的支持

摘　　要：目的:探讨精神分裂症患者与分裂型人格个体的时间加工行为特征。方法:选取59名符合美国精神障碍诊断与统计手册第4版(DSM-IV)精神分裂症诊断标准的门诊或住院患者,62名通过分裂型人格问卷(SPQ)筛查的分裂型人格个体以及60名健康对照人群。通过时间辨别任务、时间产生任务、时间复制任务对3组被试的时间加工能力进行测查。结果:时间产生任务中,分裂型人格组的准确性得分大于健康对照组[(1.03±0.07)vs.(0.99±0.09),P<0.05],精神分裂症组的变异系数大于健康对照组和分裂型人格组[(0.26±0.10)vs.(0.20±0.05),(0.20±0.05);均P<0.01];时间复制任务中,精神分裂症组的变异系数大于健康对照组和分裂型人格组[(0.21±0.11)vs.(0.15±0.07),(0.17±0.12);均P<0.01)。结论:精神分裂症患者和分裂型人格个体都存在时间加工表现上的缺损,其中精神分裂症患者的缺损可能更为严重。Objective： Schizophrenia is associated with time-processing impairments. However, very little is known about this type of problem in at-risk individuals with schizotypal personality disorder （SPD） features. The current study compared time-processing performance in patients with schizophrenia, individuals with SPD features, and healthy controls. Methods： A number of tasks capturing time discrimination, time production and time reproduction as well as other related abilities were administered to 59 schizophrenia patients, 62 individuals with SPD fea- tures, and 60 healthy controls. The diagnosis was made according to the Diagnostic and Statistical Manual of Mental Disorders-IV, Fourth Edition （DSM-IV） criteria. In analyzing the time-processing data, repeated measures were a- dopted, with group as a between-subjects variable, duration of time as a within-subjects variable, time threshold in time discrimination, accuracy （estimated time/standard time） and coefficient of variation （SD of estimated time/ mean of estimated time） of time production and time reproduction as dependent variables. Results： The result showed that patients with schizophrenia, SPD individuals and healthy controls had similar time discrimination threshold （P 〉 0. 05）. In the time production task, SPD individuals had higher accuracy score than healthy controls [ （ 1.03 ±0. 07） vs. （0. 99± 0. 09）, P 〈 0. 05 ], while patients with schizophrenia had higher coefficient of variation as compared to individuals with SPD features and healthy volunteers[（0. 26 ±0. 10） vs. （0. 20 ±0. 05）, （0. 20 ± 0. 05） ; Ps 〈 0. 01]. In the time reproduction task, patients with schizophrenia also scored higher on the coefficient of variation than SPD individuals and healthy controls[ （0.21 ± 0. 11） vs. （0. 15± 0.07）, （0. 17 ±0. 12）; Ps 〈0. 01]. Conclusion： The current findings suggest that both SPD individuals and patients with schizophrenia may have impairments on time processing. The impairment

关 键 词：时间加工 精神分裂症 分裂型人格 混合实验设计 

分 类 号：R749.3[医药卫生—神经病学与精神病学]