神经外科术后颅内感染相关因素、感染菌谱及耐药性的研究  

The related factors of postoperative intracranial infections in neurosurgery and the distribution and antibiotic resistance of bacteria in patients with postoperative intracranial infections

作　　者：高勇[1] 李秀芹[1] 王泉相[1] 李普贤[1] 

机构地区：[1]山东省莱芜市人民医院神经外科,271100

出　　处：《中国医疗前沿》2013年第11期68-69,共2页China Healthcare Innovation

摘　　要：目的探讨神经外科术后颅内感染相关因素、感染菌谱及耐药分布情况,为临床预防控制神经外科术后颅内感染提供可靠依据。方法回顾性分析2006年1月-2011年12月本院1600例神经外科手术患者,对术后颅内感染相关的各项因素、常见感染细菌及耐药性进行分析研究。结果 1600例入选病例中感染151例,感染率9.44%;通过头皮拭子及脑脊液标本培养及药物敏感试验,确认颅内感染常见致病菌及敏感药物。结论神经外科术后颅内感染涉及多因素,以各种原因所致颅内外交通等为常见因素。神经外科术后感染以革兰氏阳性球菌多见,临床经验用药应以针对革兰氏阳性球菌的广谱抗生素为主。Objective To investigate the factors of postoperative intracranial infections in neurosurgery and the distribution and antibiotic resistance of bacteria in patients with postoperative intracranial infections,and to provide valuable information for prophylactic and empirical antibiotic use in postoperative intracranial infection.Methods Totally 1600 patients who had a neurosurgical operation from Jan 2006 to Dec 2011 were chosen.Most related factors that may cause infection were studied retrospectively.At equal pace to studied common infection bacterial and bacterial antibiotic resistance.Results Totally 151 cases of 1600 patients were diagnosed as postoperative intracranial infection,infection rate is 9.44%.To confirm common infection pathogenic bacterium and sensitive drug through cultivation of scalp specimens and cerebrospinal fluid,drug sensitivity test.Conclusions Postoperative intracranial infections of neurosurgery involve in many factors.The most factor is communication of Intracranial and extracranial.The prevailing pathogenic bacterium in postoperative intracranial infection are Gram-positive cocci.Broad-spectrum antibiotic for Gram-positive cocci is prefer.

关 键 词：神经外科 颅内感染 相关因素 抗生素 耐药菌株 

分 类 号：R741.05[医药卫生—神经病学与精神病学]