矢车菊-3-葡萄糖的抗癌效应研究进展  

Research Progress in Anticancer Effect of Cyanidin-3-glucoside

作　　者：陈亮[1,2] 辛秀兰[2] 袁其朋[1] 

机构地区：[1]北京化工大学化工资源有效利用国家重点实验室,北京100029 [2]北京电子科技职业学院生物工程学院,北京100029

出　　处：《食品科学》2013年第13期329-333,共5页Food Science

基　　金：国家公益性行业(农业)科研专项(201103037);北京市属高等学校人才强教深化计划资助项目;北京市职业院校职教名师资助项目

摘　　要：花色苷是一类天然的黄酮类化合物,广泛分布在人们日常饮食的水果蔬菜中。大量的流行病学与动物实验研究表明花色苷具有癌症化学预防作用。本文总结了在大多数浆果及相关产品中分布最普遍、含量高的花色苷-矢车菊-3-葡萄糖苷的抗癌效应,这种效应主要通过抗氧化、激活Ⅱ相解毒酶、抗细胞增殖、诱导细胞凋亡、抗炎效应、抗血管生成、抗细胞侵入、诱导细胞分化等机制来发挥,本文概述了矢车菊-3-葡萄糖苷的癌症预防效应。Anthocyanins are a group of naturally occurring flavonoid compounds,which is widely available in fruits and vegetables in human diets.A lot of epidemiological and animal experiments have demonstrated that anthocyanins may contribute to cancer chemoprevention.In this article,we summarize the anti-cancer effects and the mechanisms of anthocyanins and cyanidin-3-glucoside（C3G） in berries and related food products on several key steps： antioxidant effects,enzyme activation,anti-cell proliferation,apoptosis induction,anti-inflammation,anti-angiogenesis,anti-invasiveness,and differentiation induction.This review provides a molecular view of cyanidin-3-glucoside contributing to cancer chemoprevention.

关 键 词：花色苷 矢车菊-3-葡萄糖苷 抗癌效应 

分 类 号：TS255.1[轻工技术与工程—农产品加工及贮藏工程]