CT显示无症状腔隙性与有症状非腔隙性脑梗死的影响因素差异分析  

Differences of risk factors of asymptomatic lacunar infaction and symptomatic nonlacunar infaction diagnosed by CT

作　　者：刘小玲[1] 冯广森[1] 阮君[1] 裴高油[1] 

机构地区：[1]郑州大学第二附属医院放射科,郑州450014

出　　处：《中华神经医学杂志》2013年第8期810-814,共5页Chinese Journal of Neuromedicine

摘　　要：目的 通过对无症状腔隙性脑梗死的患者以及有症状非腔隙性脑梗死的患者的危险因素进行比较分析,初步探讨这两类疾病的发病机制异同. 方法 选取郑州大学第二附属医院体检中心进行健康检查的年龄在50岁以上的体检者共1989例,检查出48例无症状腔隙性脑梗死（A组）以及51例有症状非腔隙性脑梗死（B组）分别与1862例非脑血管病对照组进行危险因素的单因素分析,然后进行多因素分析,再在两病例组间进行危险因素分布的比较以及数量的比较分析.结果 经过单因素及多因素分析后得到年龄、高血压及吸烟是无症状腔隙性脑梗死的独立危险因素（P＜0.05）,而有症状非腔隙性脑梗死的独立危险因素是年龄、性别、糖尿病、酗酒、卒中家族史及颅内动脉狭窄（P＜0.05）.组间比较显示糖尿病和颅内动脉动脉狭窄在两组间的分布差异具有统计学意义（糖尿病x2=17.603,P=0.008;颅内动脉狭窄：,x2=19.319,P=0.005）.有症状非腔隙性脑梗死的危险因素数量明显多于无症状腔隙性脑梗死,差异具有统计学意义（Z=2598,P=0.009）. 结论 无症状腔隙性脑梗死和有症状非腔隙性脑梗死的危险因素存在差异,而血管机制有所不同,糖尿病及颅内动脉狭窄在有症状非腔隙性脑梗死中更多见.Objective To investigate the different pathogeneses of asymptomatic lacunar infaction and symptomatic nonlacunar infaction by investigating their risk factors.Methods A total of 1989 people more than 50 years old,performed physical examination were chosen with the results showing 48 patients with asymptomatic lacunar infaction （group A） and 51 patients with symptomatic nonlacunar infaction （group B）.Another 1862 controls without cerebrovascular disease were also chosen.Single factor analysis and logistic regression analysis were used to analyze the risk factors.Each risk factor and amount of risk factors for the two diseases was compared between group A and group B.Results Age,hypertension and smoking were the independent predictors of asymptomatic lacunar infaction （P〈0.05）.Age,sex,diabetes mellitus,drinking,family history of stroke and stenosis of intracrianial artery were the independent predictors of the symptomatic nonlacunar infaction （P〈0.05）.Both rates of diabetes mellitus and stenosis of intracrianial artery in group B were higher than those in group A （diabetes mellitus：x2=17.603,P=0.008; stenosis of intracrianial artery：x2=19.319,P=0.005）.The amount of risk factors in patients from group B was significantly more than that in patients from group A （Z=2598,P=0.009）.Conclusion The risk factors and vascular mechanism in patients with symptomatic nonlacunar infaction and asymptomatic lacunar infaction are different.Diabetes mellitus and stenosis of intracrianial artery are more often noted in patients with symptomatic nonlacunar infarction.

关 键 词：无症状腔隙性脑梗死 有症状非腔隙性脑梗死 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]