微型营养评定法在老年慢性阻塞性肺疾病患者中的应用及其与BODE指数的相关性  

Application of Mini Nutritional Assessment in patients with chronic obstructive pulmonary disease and its correlation with BODE indexes

作　　者：孙嘉[1] 郑晶晶[2] 郭松文[2] 朱哲[2] 陈新[2] 

机构地区：[1]南方医科大学珠江医院内分泌科,广东广州510282 [2]南方医科大学珠江医院呼吸内科,广东广州510282

出　　处：《南方医科大学学报》2013年第8期1217-1220,共4页Journal of Southern Medical University

基　　金：广东省自然科学基金博士科研启动基金(S2012040006903);广东省科技计划社会发展项目(E002009062);广东高校优秀青年创新人才培育项目(LYM08033)

摘　　要：目的探讨微型营养评定法（MNA）在老年慢性阻塞性肺疾病（COPD）患者中的应用,分析其与BODE指数的相关性。方法选择2012年4月~10月南方医科大学珠江医院呼吸内科门诊稳定期COPD老年患者139例,采用MNA评估营养状态并分为营养良好组、营养风险组及营养不良组。测定患者的体测指标、肺功能、6分钟步行距离（6MWD）,采用MMRC评估呼吸困难程度。按BODE指数评分标准进行评分,并分析其与MNA评分间的相关性。结果 3组间性别构成无统计学意义（P〉0.05）,年龄及体测指标差异具统计学意义（P〈0.001）。3组间BODE指数参数FEV1%Pred、BMI、MMRC、6MWD的评分情况差异均有统计学意义（P〈0.001）。MNA评分与BODE指数呈负相关（r=-0.605,P〈0.001）。结论 MNA与体测指标、BODE指数密切相关,适用于COPD人群;营养是COPD患者症状的重要影响因素,改善营养状态是缓解症状的有效措施之一。Objective To evaluate the value of Mini Nutritional Assessment(MNA) in geratic patients with chronic obstructive pulmonary disease(COPD) and analyze the correlation of MNA scores with BODE indexes.Methods A total of 139 geratic outpatients with stable COPD admitted from April 2012 to October 2012 were enrolled.The nutritional statuses of the patients were assessed using MNA and the patients were subsequently classified into well-nourished group,risk of malnutrition group and malnutrition group.For all the patients,the anthropometric parameters,pulmonary function and 6-minute-walk distance(6MWD) were examined,and functional dyspnea was evaluated using Modified Medical Research Council Scale(MMRC).The BODE indexes were calculated and analyzed for their correlation with the MNA scores.Results The 3 groups showed no significant differences in gender distribution(P>0.05),but their age,anthropometric parameters and BODE indexes(BMI,MMRC,6MWD,FEV1% pred) differed significantly(P<0.001).In all the patients,MNA scores showed a significant inverse correlation with BODE index(r=-0.602;P<0.001).Conclusion MNA scores are strongly correlated with the anthropometrical parameters and BODE indexes to allow screening of the nutritional status in patients with COPD.Nutrition is an important factor affecting the disease symptoms,and nutritional improvement is one of the effective measures to relieve the symptoms of COPD.

关 键 词：慢性阻塞性肺疾病 营养 微型营养评定法 BODE指数 

分 类 号：R563.9[医药卫生—呼吸系统]