重症急性胰腺炎并发中毒性表皮坏死松解症的诊断和治疗  

Diagnosis and treatment of severe acute pancreatitis compli- cated with toxic epidermal necrolysis

作　　者：伏添 童智慧[2] 李维勤[2] 

机构地区：[1]陕西省汉中市三二○一医院重症医学科,723000 [2]南京军区南京总医院普通外科SICU,210000

出　　处：《中华消化外科杂志》2013年第8期634-636,共3页Chinese Journal of Digestive Surgery

基　　金：国家自然科学基金（81200334）

摘　　要：中毒性表皮坏死松解症（TEN）是一种急性皮肤炎症反应，属于重型药疹的一类。随着抗生素、非甾体类解热镇痛等药物在救治危重患者中的广泛应用，TEN在临床上，特别是ICU病房中其发病率有增高趋势。TEN病死率较高，且对危重患者的整体预后有较大影响。本文报道南京军区南京总医院普通外科收治的1例重症急性胰腺炎患者，应用阿司匹林预防血栓及栓塞并发症过程中并发TEN，总结该病的诊断和治疗经验以供临床医师参考。Toxic epidermal necrolysis （TEN） is an acute skin inflammation, which belongs to heavy drug eruption. With the extensive and widespread use of antibiotics, nonsteroi- dal antipyretic analgesics and other pharmacotherapies in the treatment of critically ill patients, the trend of morbidity of TEN is gradually increased, especially in intensive care unit. In con- sideration of the high mortality rate of TEN and its great influence on the overall prognosis of patients with critical illness, we sum- marized the diagnosis and treatment experiences in the manage- ment of TEN based on retrospective analysis of one patient with severe acute pancreatitis and TEN.

关 键 词：重症急性胰腺炎 表皮坏死松解症 中毒性 阿司匹林 

分 类 号：R576[医药卫生—消化系统]