^(99m)Tc-MIBI乳腺显像检测乳癌及腋淋巴结转移  

Detection of primary breast cancer and axillary lymph node metastasis by^(99m)Tc-MIBI prone scintimamorgaphy

作　　者：杨学伟[1] 金刚[1] 王志春[1] 杨维良[1] 

机构地区：[1]哈尔滨医科大学第二附属医院普外科,黑龙江哈尔滨150086

出　　处：《中国普通外科杂志》2000年第6期538-540,共3页China Journal of General Surgery

摘　　要：目的　前瞻性评价99mTc 甲氧基异丁基异腈 (99mTc MIBI)乳腺显像检测原发性乳癌和腋淋巴结转移的灵敏度和特异性。方法　 84例经临床病理学检查可疑乳癌妇女 ,应用99mTc MIBI进行乳腺平面俯卧左、右侧位和仰卧前位显像 ,每一体位采集时间 5～ 8min。乳房和腋窝区域包括在采集视野内。切除的乳腺和腋淋巴结的病理检查均在乳腺显像后 10d内进行。结果　乳腺平面显像检测原发性乳癌的灵敏度为 90 2 % (4 6 / 5 1) ,特异性为93 93 % (31/ 33)。 5 1例乳腺癌中有 2 5例发生腋淋巴结转移 ,乳腺显像检测腋淋巴结转移的灵敏度为 84% (2 1/ 2 5 ) ,特异性为 88 46 % (2 3/ 2 6 )。Objective To prospectively study the sensitivity and specificity of 99m Tc Methoxyisobutyl Isonitrile( 99m Tc MIBI) scintimammorgaphy in the detection of both primary breast cancer and axillary lymph node metastasis. Methods Eighty four consecutive women suspicious of breast cancer under clinical examination were checked by the scintimammorgaphy of planar prone imaging in three planar views(5～8?min/view). The entire breast and ipsilateral axillary region were included in the field of view. Biopsy of resectional breast and lymph node were performed within 10 days after scintimammography. Results There were 51 primary breast cancer(7 different histologic types) and 33 benign breast lesion(4 histologic types) in this series. The sensitivity of scintimammography for detecting primary breast cancer was 90.20%(46/51) and the specificity was 93.93%(31/33). Metastatic axillary lymph nodes were seen in 25 of the 51 patients. The sensitivity of scintimammography to detect metastatic lymph node was 84.0%(21/25) and the specificlty was 88.46%(23/26). Conclusions The results of this study indicate that the scintimammography has high diagnosis rate in detecting breast cancer and axillary lymph node metastasis.

关 键 词：乳腺肿瘤/放射照相术 淋巴结转移/放射照相术 腋/放射照相术 ^(99m)Tc甲氧基异丁基异腈/诊断应用 

分 类 号：R737.9[医药卫生—肿瘤]