脑通口服液治疗脑梗塞家兔的阻抗脑血流图变化  

Rheoencephalography Study of Treatment with Naotong Oral Solution on Acute Cerebral Embolism in Rabbits

作　　者：唐可欣[1] 王凤斌[1] 唐可清[2] 田立[2] 

机构地区：[1]潍坊医学院生理学教研室,山东潍坊261042 [2]潍坊市中医院

出　　处：《潍坊医学院学报》2000年第4期256-257,共2页Acta Academiae Medicinae Weifang

基　　金：山东省中医药管理局课题!(课题号 :1 996年 0 1 0 6号 )

摘　　要：目的　观察急性脑梗塞家兔应用脑通口服液治疗前后对脑血流图的影响。方法　脑梗塞家兔模型 2 0只随机分为脑通口服液治疗组和生理盐水对照组 ,观察两组动物治疗前后脑血流图的变化 ;结果　与治疗前比较 ,脑通口服液组经治疗 10 d后其脑血流图的流入时间缩短 ( P<0 .0 5) ,波幅明显增高( P<0 .0 1) ,与盐水对照组比较 ,该两项指标差异有显著性 ( P<0 .0 5,P<0 .0 1) ;结论　脑通口服液在脑梗塞急性期可明显降低脑血流阻力 ,增加梗塞侧半球脑组织的血液灌流量 ,从而减轻脑组织因缺血造成的损伤 ,适用于脑梗塞急性期的治疗。Objective To observe the effect of Naotong oral solution (NTOS) on rheoencephalography (REG) in acute cerebral embolism rabbits.Method 20 rabbits of acute cerebral embolism were divided into two groups,which were respectively treated with NTOS and normal saline (NS) for 10 days.REG in two groups were recorded and observed before and after treatment.Result After above treatment,the inflow time of REG were shortened and the amplitude were raised in NTOS group.There was a significant difference between the two groups (P<0.05 inflow time,P<0.01 amplitude).The same result appeared in NTOS group before and after treated with NTOS (P<0.05 inflow time,P<0.01 amplitude).Conclusion NTOS may reduce the resistance of brain bloodstream in acute cerebral embolism and increase the blood flow of embolism brain,so it can reduce the cerebral damage caused by ischemia and may be used to treat acute cerebral embolism. [

关 键 词：脑通口服液 脑梗塞 阻抗脑血流图 治疗 

分 类 号：R743.330.5[医药卫生—神经病学与精神病学]