Nickel-Catalyzed ortho-Selective Hydrodefluorination of N-Containing Heterocycle-Polyfluoroarenes  

作　　者：Yi He Zhao Chen Chun-Yang He Xingang Zhang 

机构地区：[1]State Key Lab of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, 8 Xindu Avenue, Chengdu, Sichuan 610500, China [2]Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China [3]School of Chemistry and Chemical Engineering, Southwest Petroleum University, 8 Xindu Avenue, Chengdu, Sichuan 610500, China

出　　处：《Chinese Journal of Chemistry》2013年第7期873-877,共5页中国化学（英文版）

摘　　要：An effective and facile method for preparation of partially fluorinated aromatics via Nickel catalyzed, chelation-assisted ortho selective hydrodefluorination of polyfluoroames with triethylsilane has been developed, in which N-containing heterocycles were used as directing groups. The advantage of this protocol is its simple catalytic system with use of inexpensive and readily available NiCl2·6H2O as a catalyst.An effective and facile method for preparation of partially fluorinated aromatics via Nickel catalyzed, chelation-assisted ortho selective hydrodefluorination of polyfluoroames with triethylsilane has been developed, in which N-containing heterocycles were used as directing groups. The advantage of this protocol is its simple catalytic system with use of inexpensive and readily available NiCl2·6H2O as a catalyst.

关 键 词：catalytic C--F activation HYDRODEFLUORINATION nickel POLYFLUOROARENES triethylsilane 

分 类 号：TQ333.2[化学工程—橡胶工业] TE626.21[石油与天然气工程—油气加工工程]