奥尔芬联合间苯三酚治疗急性胆绞痛疗效分析  

Combined effects of olfen and phloroglucinol in patients with acute biliary colic

作　　者：宋厚梅[1] 胡浩[1] 孙婧婧[1] 

机构地区：[1]江苏省无锡市第三人民医院,江苏无锡214000

出　　处：《实用临床医药杂志》2013年第9期91-92,97,共3页Journal of Clinical Medicine in Practice

摘　　要：目的评价奥尔芬联合间苯三酚治疗胆绞痛的疗效及安全性。方法将2011年3月—2012年3月于本院就诊的120例胆绞痛患者随机分为4组,每组30例。A组给予奥尔芬+间苯三酚,B组给予奥尔芬,C组给予间苯三酚,D组给予山莨菪碱。比较各组镇痛效果及不良反应发生率。结果 A、B、C、D组的镇痛总有效率分别为100.0%、76.7%、66.7%、33.3%。A组与B、C、D组镇痛效果相比较,差异有统计学意义(P<0.05);B组与C组相比较,差异无统计学意义(P>0.05);B组及C、D组相比较,差异均有统计学意义(P<0.05)。A、B、C、D组的不良反应发生率分别为6.7%、6.7%、3.3%、53.3%。A、B、C组组间比较,差异无统计学意义(P>0.05);A、B、C组与D组相比较,差异均有统计学意义(P<0.05)。结论奥尔芬联合间苯三酚治疗急性胆绞痛,疗效确切,不良反应少,值得临床推广应用。Objective To evaluate the curative effect and safety of olfen and phloroglucinol in patients with acute biliary colic.Methods A total of 120 patients with acute biliary colic of our hospital from March 2011 to March 2012 were divided into four groups randomly,group A（Olfen and Phloroglucinol,n=30）,group B（olfen,n=30）,group C（phloroglucinol,n=30）,and group D（anisodamine,n=30）.The analgesic effect and adverse reaction of four groups were observed.Results The total effectiveness rates of analgesia in groups A,B,C and D were 100%,76.7%,66.7% and 33.3%,respectively.The differences were statistically significant between group A and other three groups（P0.05）.There were no statistical differences between group B and group C（P0.05）,and the differences were statistically significant between group B and group C and D（P0.05）.The adverse reaction rates of groups A,B,C and D were 6.7%,6.7%,3.3% and 53.3%,respectively.There were no statistical differences in groups A,B and C（P0.05）,and the differences were statistically significant between group D and other three groups（P0.05）.Conclusion Combined application of olfen and phloroglucinol in patients with acute biliary colic results in noticeable analgesic effect and fewer side effects.Thus it is worth clinical applications.

关 键 词：奥尔芬 间苯三酚 胆绞痛 

分 类 号：R575[医药卫生—消化系统]