促甲状腺激素抑制疗法在分化型甲状腺癌治疗中的作用  

Value of thyroid stimulating hormone inhibition therapy in differentiated thyroid carcinoma

作　　者：李志红[1] 

机构地区：[1]湖北省鄂州市中心医院肿瘤科,湖北鄂州436000

出　　处：《实用临床医药杂志》2013年第9期107-108,共2页Journal of Clinical Medicine in Practice

摘　　要：目的探讨促甲状腺激素(TSH)抑制疗法在分化型甲状腺癌患者术后治疗中的作用。方法 130例分化型甲状腺癌患者于甲状腺切除术后分别行TSH抑制治疗(观察组)和甲状腺素替代治疗(对照组),比较2组患者术后无复发和/或无转移率。结果观察组术后3、5、10年的无复发和/或无转移率分别为98.76%、93.21%及79.54%,对照组分别为92.17%、82.36%及51.25%,2组差异有统计学意义(P<0.05)。结论 TSH抑制疗法是分化型甲状腺癌患者行全或近全甲状腺切除术后的有效治疗手段。Objective To investigate the value of thyroid stimulating hormone（TSH） inhibition therapy in postoperative patients with differentiated thyroid carcinoma.Methods One hundred and thirty patients with differentiated thyroid carcinoma after total or near-total thyroidectomy were divided into two groups： TSH inhibition therapy group（the observation group） and thyroid hormone replacement therapy group（the control group）.The non-recurrence and（or） non-metastasis rate of the two groups were analyzed.ResultsThe non-recurrence and（or） non-metastasis rate of 3-,5-and 10-year in TSH inhibition therapy group were 98.76%,93.21% and 79.54%,and those of the thyroid hormone replacement therapy group were 92.17%,82.36% and 51.25%.There were statistically significant difference between the two groups（P0.05）.Conclusion TSH inhibition therapy after total or near-total thyroidectomy may be an essential treatment for differentiated thyroid carcinoma patients.

关 键 词：分化型甲状腺癌 促甲状腺激素抑制疗法 甲状腺素替代治疗 

分 类 号：R736.1[医药卫生—肿瘤]