胃肠道间质瘤诊治体会  

The experience of diagnosis and treatment of gastrointestinal stromal tumor

作　　者：赵海俊[1] 赵臣[1] 宋强[1] 陈志东[1] 

机构地区：[1]内蒙古包头医学院第三附属医院普外科,内蒙古包头014030

出　　处：《世界最新医学信息文摘》2013年第9期49-50,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨胃肠道间质瘤（GIST）的发病情况、病理特点、诊断和治疗方法。方法采集包头医学院第三附属医院2007年01月至2013年5月期间就诊患者共146例，进行回顾性分析。结果发病情况男80例，女66例；本组患者因肿瘤不同的生长部位临床表现也各异；术后病理及免疫组化结果CD117（＋）132例（90．4％），CD34（＋）122例（84．0％），S100（＋）25例（17．1％），actin（＋）29例（19．9％）。结论胃肠道间质瘤男女发病率相似，主要集中在中老年；GIST在病理上绝大部分表现为CD117（＋）和CD34（＋）；GIST临床表现多样化，术前能明确诊断的很少，绝大部分通过术后病理确诊；GIST最有效的治疗方法是手术完整切除。Objective to study the ill information, features pathology, diagnosis and treatment of gastroinstestinal stromal tumor（GIST）. Methods： from January 2007 to May 2013, The clinicalpathoIogic and clinical data were analyzed retrospectively. Results The Incidence of the disease is similar in females and males; The clinical presentations were different with tumor sites; CD 117（＋） 132 （90.4%）,CD34（＋） 122 （84.0%）,S- 100（＋）25 （17.1%）, actin（＋）29（19.9%）. After the surgeon 85 are returned a visit 63 of 85（74.1%）are well,and 22 Of 85 （25.9%）are dead, 45 of 63 keep review after surgeon ,9 Of 63 keep imatinib over 1 year. The 22 of 85 are dead after surgeon because relapse and metastasis. Conclusion The years are main middle-aged and elderly; GIST pathology mainly as CD117（＋） andCD34（＋）; Clinical symptoms for patients of GIST have no specific before surgery to confirm the diagnosis very little, mostly through the postperative pathological diagnosis. GIST most effective treatment is surgical remove.

关 键 词：胃肠道间质瘤 临床特点 诊断治疗 

分 类 号：R735[医药卫生—肿瘤]