内镜下卢戈氏液染色对早期食管癌及癌前病变的诊断价值  

Diagnostic analysis of endoscopic Lugol liquid staining for early esophageal cancer and precancerous lesions

作　　者：李琪毅[1] 姜仕柱[1] 李素玉[1] 

机构地区：[1]三峡大学仁和医院消化内科,湖北宜昌443001

出　　处：《实用临床医药杂志》2013年第15期26-28,共3页Journal of Clinical Medicine in Practice

摘　　要：目的探讨卢戈氏液染色对早期食管癌及癌前病变的诊断价值。方法对本院内镜室2011年11月—2013年4月的187例患者的食管表浅病灶进行卢戈氏液染色,并行病理学检查,将病理结果与染色结果进行对比。结果 187例患者中经病理确诊为食管鳞癌41例,食管重度不典型增生9例,食管中度不典型增生33例,食管轻度不典型增生15例,慢性食管炎58例,鳞状上皮增生31例。卢戈氏液染色后食管癌及癌前病变主要表现为卢戈氏液不染和淡染,卢戈氏液淡染和不染诊断食管癌与癌前病变的准确性为62.82%(98/156);食管癌和食管重度不典型增生主要表现为卢戈氏液不染,其准确性高达95.6%(45/48)。结论内镜下卢戈氏液染色对鉴别食管癌、癌前病灶与炎性病灶等具有十分重要的临床价值。Objective To investigate the clinical and pathological diagnosis of Lugol solution to early esophageal cancer and precancerous lesions. Methods One hundred and eightyseven patients with suspicious lesions of esophageal endoscopy in our hospital from Nov. 2011 to Apr. 2013 were chosen as study objects and were dyed with Lugol of the liquid and were given pathological examination. Pathology results and the results of dye were compared. Results Fortyone out of the 187 cases were found with esophageal squalors carcinoma, 9 with severe esophageal dysplasia, 33 with moderate esophageal dysplasia, 15 with esophageal mild dysplasia, 58 with chronic esophagi, 3l with squalors cell hyperplasia. After Lugol solution dyeing, the signifying of esophageal cancer and precancerous lesions was not pollution or light pollution, and the accuracy was 62.82 %. LugoI non-staining liquid esophagus and esophageal cancer diagnosis of severe dysplasia was as high as 93.75% in accuracy. Conclusion Endoscopic Lugol solution staining confined with superficial esophageal biopsy of the lesion have important value in diagnosing superficial esophageal lesion.

关 键 词：卢戈氏液染色 食管癌 癌前病变 诊断 

分 类 号：R735.1[医药卫生—肿瘤]