肌肉松弛对神经再生与传导作用的实验研究  

Experimental study of the effects of skeleton muscular relaxation on nerve conduction and regeneration

作　　者：王天兵[1] 陈德松[1] 方有生[1] 陈琳[1] 彭峰[1] 张鸿振[2] 

机构地区：[1]上海医科大学华山医院手外科,200040 [2]浙江省温州市第五人民医院

出　　处：《中华骨科杂志》2000年第10期610-613,共4页Chinese Journal of Orthopaedics

摘　　要：目的了解小鼠骨骼肌松弛是否能改善神经传导 ,加快损伤神经的再生。方法取昆明小鼠 96只，建立肌皮神经损伤模型，随机分为肌松组、肌松加神经营养药组、神经营养药组和对照组。通过对神经的电生理检查、肌肉湿重测量及损伤神经远端有髓神经纤维计数的方法，评估骨骼肌松弛是否有利于神经的传导和损伤神经的再生。结果肌松组小鼠神经传导和损伤神经的再生与神经营养药组接近，优于对照组。结论骨骼肌松弛有改善神经传导、加快损伤神经再生的作用。Objective To study the effects of skeleton musclular relaxation on nerve conduction and regeneration. Methods Musclocontaneous nerve injury model was established in 96 mice and the animals were divided into skeleton muscle relaxation, skeleton muscle relaxation and neurotrophic drugs, neurotrophic drugs and control group. Nerve conduction and regeneration were evaluated by electromyography; muscle weight and counting of distal regenerated myelinated nerve fibers. Results The velocity of nerve conduction and regeneration in skeletal muscle group was the same as that in skeleton muscle relaxation and neurotrophic group, and higher than that in control group. Conclusion Skeleton muscle can enhance nerve conduction and regeneration.

关 键 词：周围神经 损伤 神经再生 神经传导 肌肉松驰 

分 类 号：R363[医药卫生—病理学]