正常人尿中单羟酚类物质含量的测定研究  

DETERMINATION THE LEVEL OF MONOHYDROXYPHENYL SUBSTANCES IN NORMAL HUMAN URINE

作　　者：侯华新[1] 梁永红[1] 赵农[1] 黄燕军[1] 李福森[1] 宋慧[1] 雷耀兴[1] 

机构地区：[1]广西医科大学化学教研室,南宁530021

出　　处：《广西医科大学学报》2000年第5期754-755,共2页Journal of Guangxi Medical University

基　　金：广西壮族自治区自然科学基金!资助课题 ( 973 2 0 3 2 )

摘　　要：目的 :确定正常人尿中单羟酚衍生物 (MHP)含量范围。方法 :采用可见分光光度法 ,定量测定 18～ 6 0岁各类正常人及 HBs Ag阳性携带尿液中单羟酚类物质。结果 :MHP含量与年龄、性别有一定的关系 ,194例健康人尿中 MHP含量为正态分布 ,第 95百分位数的 OD值上限为 0 .3,对应酪氨酸含量是 2 .46 m mol/ L。而 HBs Ag阳性携带者尿液 MHP与正常人无显著性差异。结论 :此实验结果在运用 MHP进行肿瘤筛查时 。Objective:To determine the normal range of Monohydroxyphenyl substances (MHP) level in human urine Method:Monohydroxyphenyl substances level in human urine which collected from normal persons and HBsAg carrying persons were detected quanititatively by visable spectophotometer method Results:The results indicated that there was a little different between the differential sex group and the age group The urine samples from194 healthy subjects (the age from 18~60 years) were determined to establish a reference range of urinary MHP (confidence interval 95%),and its upper limit was 2 46mmol/L,when Tyr was selected as the standard There was not remarkable different between the normal persons and the HBsAg carrying persons Conclusion:The assay results can be considered as a normal range of urinary MHP when this method is used a cancer screening system

关 键 词：单羟酚类物质 尿液 正常人 

分 类 号：R446.122[医药卫生—诊断学]