Ⅱ型糖尿病与肠道菌群及益生菌的相关性研究进展  

Research progress on relationship between type 2 diabetes, gut microbiota and probiotics

作　　者：郭霄[1] 张勇[1] 郭建林[1] 孙天松[1] 

机构地区：[1]内蒙古农业大学乳品生物技术与工程教育部重点实验室,呼和浩特010018

出　　处：《中国乳品工业》2013年第8期48-51,共4页China Dairy Industry

基　　金：内蒙古自治区科技计划项目(209-202060)

摘　　要：Ⅱ型糖尿病是一种常见的慢性代谢性疾病,其发病机制十分复杂,其中肠道菌群在其发病早期和加重过程中都起着重要的作用。益生菌作为调节肠道菌群的有效手段,可以通过改善肠道通透性、调节血脂、增强机体免疫力等多种机制对II型糖尿病起到预防和改善作用。现就近年来肠道菌群和2型糖尿病的相关性以及益生菌的作用研究进展作一综述。Type 2 diabetes is a common chronic metabolic diseases with complex pathogenesis, Gut microbiota plays an important role in the early onset and deterioration of the diabetes.As an effective means of regulating gut microbiota, probiotics are living organisms that are primari- ly used in the prevention and alleviation of type 2 diabetes by improving the intestinal permeability, regulating the serum lipids, enhancing im- munity and other mechanisms. In this review,we discuss the research advance about links between the gut microbiota and type 2 diabetes as well as the role of probiotics in recent years.

关 键 词：II型糖尿病 肠道菌群 益生菌 

分 类 号：R587.1[医药卫生—内分泌] TS201.3[医药卫生—内科学]